Study of some Antioxidants in plasma of patients with bladder cancer

The objective of this study was to determine the catalase activity (CAT),ceruloplasmin activity (CP), glutathione level (GSH) in the plasma of (44) normaldonars (22 male, 22 female,) and (66) patients with bladder cancer (22 smoker male, 22non smoker male, 22 female). Data analysis showed a signific...

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Main Authors: Israa G. Zainal, Mhammed AL-Dori, Abdul-Nasser M. Abdula
Format: Article
Language:English
Published: Unviversity of Technology- Iraq 2009-03-01
Series:Engineering and Technology Journal
Subjects:
Online Access:https://etj.uotechnology.edu.iq/article_29238_9a78fcc522c935784d4a2a0029e79be2.pdf
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author Israa G. Zainal
Mhammed AL-Dori
Abdul-Nasser M. Abdula
author_facet Israa G. Zainal
Mhammed AL-Dori
Abdul-Nasser M. Abdula
author_sort Israa G. Zainal
collection DOAJ
description The objective of this study was to determine the catalase activity (CAT),ceruloplasmin activity (CP), glutathione level (GSH) in the plasma of (44) normaldonars (22 male, 22 female,) and (66) patients with bladder cancer (22 smoker male, 22non smoker male, 22 female). Data analysis showed a significant decrease in the meanvalues of CAT (89.577 ± 17.140 of a smoker male, 92.102 ± 18.898 of non-smokermale, 90.225± 12.997 of a female) as compared to normal individuals (155.541 U/mgHb of a male, 150.797 U/mg Hb of a female) respectively, and GSH (0.109 ± 0.056 of asmoker male, 0.110 ± 0.051 of non-smoker male, 0.084 ± 0.028 of a female) ascompared to normal individuals (0.838 μmol/L of a male, 0.809 μmol/L of a female)respectively. A significant increase in the mean value of CP in plasma of patients withbladder cancer (56.477 ± 2.671 of a smoker male,55.602 ± 3.042 of non-smoker, 52.101± 3.212 of a female) was recorded as compared to normal individuals (43.908 IU of amale, 41.110 IU of a female) respectively, There is also a negative relationship betweenCAT & Cp and GSH & Cp levels (r = - 0.089, and r = - 0.104) respectively, while thereis a positive relationship between CAT and GSH (r = 0.081) in-patients with bladdercancer.
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spelling doaj.art-cfd1a3aed95949bfb93b039068a866af2024-02-04T17:48:59ZengUnviversity of Technology- IraqEngineering and Technology Journal1681-69002412-07582009-03-0127475175810.30684/etj.27.4.1129238Study of some Antioxidants in plasma of patients with bladder cancerIsraa G. ZainalMhammed AL-DoriAbdul-Nasser M. AbdulaThe objective of this study was to determine the catalase activity (CAT),ceruloplasmin activity (CP), glutathione level (GSH) in the plasma of (44) normaldonars (22 male, 22 female,) and (66) patients with bladder cancer (22 smoker male, 22non smoker male, 22 female). Data analysis showed a significant decrease in the meanvalues of CAT (89.577 ± 17.140 of a smoker male, 92.102 ± 18.898 of non-smokermale, 90.225± 12.997 of a female) as compared to normal individuals (155.541 U/mgHb of a male, 150.797 U/mg Hb of a female) respectively, and GSH (0.109 ± 0.056 of asmoker male, 0.110 ± 0.051 of non-smoker male, 0.084 ± 0.028 of a female) ascompared to normal individuals (0.838 μmol/L of a male, 0.809 μmol/L of a female)respectively. A significant increase in the mean value of CP in plasma of patients withbladder cancer (56.477 ± 2.671 of a smoker male,55.602 ± 3.042 of non-smoker, 52.101± 3.212 of a female) was recorded as compared to normal individuals (43.908 IU of amale, 41.110 IU of a female) respectively, There is also a negative relationship betweenCAT & Cp and GSH & Cp levels (r = - 0.089, and r = - 0.104) respectively, while thereis a positive relationship between CAT and GSH (r = 0.081) in-patients with bladdercancer.https://etj.uotechnology.edu.iq/article_29238_9a78fcc522c935784d4a2a0029e79be2.pdfcatalaseceruloplasminglutathionebladder cancer
spellingShingle Israa G. Zainal
Mhammed AL-Dori
Abdul-Nasser M. Abdula
Study of some Antioxidants in plasma of patients with bladder cancer
Engineering and Technology Journal
catalase
ceruloplasmin
glutathione
bladder cancer
title Study of some Antioxidants in plasma of patients with bladder cancer
title_full Study of some Antioxidants in plasma of patients with bladder cancer
title_fullStr Study of some Antioxidants in plasma of patients with bladder cancer
title_full_unstemmed Study of some Antioxidants in plasma of patients with bladder cancer
title_short Study of some Antioxidants in plasma of patients with bladder cancer
title_sort study of some antioxidants in plasma of patients with bladder cancer
topic catalase
ceruloplasmin
glutathione
bladder cancer
url https://etj.uotechnology.edu.iq/article_29238_9a78fcc522c935784d4a2a0029e79be2.pdf
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