Novel Affibody Molecules Specifically Bind to SARS-CoV-2 Spike Protein and Efficiently Neutralize Delta and Omicron Variants

Novel Affibody Molecules Specifically Bind to SARS-CoV-2 Spike Protein and Efficiently Neutralize Delta and Omicron Variants

ABSTRACT The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has been an unprecedented public health disaster in human history, and its spike (S) protein is the major target for vaccines and antiviral drug development. Although widespread vaccination has been well established,...

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Bibliographic Details
Main Authors: Wangqi Du, Peipei Jiang, Qingfeng Li, He Wen, Maolin Zheng, Jing Zhang, Yanru Guo, Jia Yang, Weixu Feng, Sisi Ye, Saidu Kamara, Pengfei Jiang, Jun Chen, Wenshu Li, Shanli Zhu, Lifang Zhang
Format: Article
Language:English
Published: American Society for Microbiology 2023-02-01
Series:Microbiology Spectrum
Subjects:
severe acute respiratory syndrome coronavirus 2
SARS-CoV-2
S protein
affibody
neutralization
SPR
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03562-22

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