Triflamidation of Allyl-Containing Substances:Unusual Dehydrobromination vs. Intramolecular Heterocyclization

Triflamidation of Allyl-Containing Substances:Unusual Dehydrobromination vs. Intramolecular Heterocyclization

Allyl halides with triflamide under oxidative conditions form halogen-substituted amidines. Allyl cyanide reacts with triflamide in acetonitrile or THF solutions in the presence of NBS to give the products of bromotriflamidation with a solvent interception, whereas in CH<sub>2</sub>Cl<...

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Bibliographic Details
Main Authors: Anton S. Ganin, Mikhail Yu. Moskalik, Ivan A. Garagan, Vera V. Astakhova, Bagrat A. Shainyan
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Molecules
Subjects:
allyl cyanide
allyl halides
triflamide
oxidative bromotriflamidation
solvent interception
heterocyclization
Online Access:https://www.mdpi.com/1420-3049/27/20/6910

Internet

https://www.mdpi.com/1420-3049/27/20/6910

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