Synthesis of 4′,7-Diacetoxyapigenin and Its Apoptotic Induction in Human Hep G2 Cells

Synthesis of 4′,7-Diacetoxyapigenin and Its Apoptotic Induction in Human Hep G2 Cells

In this study, 4′,7-diacetoxyapigenin [4-(7-acetoxy-5-hydroxy-4-oxo-4H-chromen-2-yl) phenyl acetate] was synthesized for the first time. Its chemical structure was identified by UV, ESI-MS, 1H and 13C-NMR. It could inhibit the proliferation of Hep G2 cells in a dose-dependent manner and induce the s...

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Bibliographic Details
Main Authors: Keyong Xu, Feng Liu, Benguo Liu, Han Gao, Zhengxiang Ning
Format: Article
Language:English
Published: MDPI AG 2010-04-01
Series:International Journal of Molecular Sciences
Subjects:
apoptosis
cell cycle
Hep G2
4′,7-diacetoxyapigenin
Online Access:http://www.mdpi.com/1422-0067/11/5/1991/

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