Influence of 2% Chlorhexidine on the Bond Strength of Three Adhesive Systems on Primary Molars: An In Vitro Study

The hydrolysis of the collagen matrix by metalloproteinases (MMPs) is one of the paradigms that currently arouses most interest due to its close relationship with a decrease in bond strength (BS) and consequent restoration failure. Chlorhexidine 2% has demonstrated its ability to inhibit MMPs’ activ...

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Main Authors: Laura Velayos-Galán, Pedro Molinero-Mourelle, Pablo Sevilla, Manrique Fonseca, María Rosa Mourelle-Martínez, Vicente Vera-González
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/12/6/2964
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author Laura Velayos-Galán
Pedro Molinero-Mourelle
Pablo Sevilla
Manrique Fonseca
María Rosa Mourelle-Martínez
Vicente Vera-González
author_facet Laura Velayos-Galán
Pedro Molinero-Mourelle
Pablo Sevilla
Manrique Fonseca
María Rosa Mourelle-Martínez
Vicente Vera-González
author_sort Laura Velayos-Galán
collection DOAJ
description The hydrolysis of the collagen matrix by metalloproteinases (MMPs) is one of the paradigms that currently arouses most interest due to its close relationship with a decrease in bond strength (BS) and consequent restoration failure. Chlorhexidine 2% has demonstrated its ability to inhibit MMPs’ activity in the permanent dentition, improving the duration of resin–dentine, but there are few studies on deciduous dentition and its possible repercussions. Aim: To determine the influence of 2% chlorhexidine digluconate (CHX) as a dentine pretreatment on the BS of three adhesive systems on primary molars. Methods: 128 primary extracted molars were assigned to eight groups at random. BS in vitro was recorded by micropush-out test, and analyzed by two-way ANOVA. Results: BS values oscillated from 15.01 MPa to 20.41 MPa. There was no statistically relevant variation between the BS total mean of those adhesive groups that had received CHX pretreatment versus those that did not. Adper Prompt L-Pop was the self-etching adhesive with the best BS. Adper Scotchbond 1XT was the total-etch adhesive with the best BS values. Conclusions: Application of 2% chlorhexidine for 60 s as dentine pretreatment did not affect the immediate BS of several adhesive systems used in primary dentition.
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spelling doaj.art-cfde1dae16154546b32b00a58f2515bd2023-11-30T20:49:29ZengMDPI AGApplied Sciences2076-34172022-03-01126296410.3390/app12062964Influence of 2% Chlorhexidine on the Bond Strength of Three Adhesive Systems on Primary Molars: An In Vitro StudyLaura Velayos-Galán0Pedro Molinero-Mourelle1Pablo Sevilla2Manrique Fonseca3María Rosa Mourelle-Martínez4Vicente Vera-González5Department of Dental Clinical Specialties, School of Dentistry, Complutense University of Madrid, 28040 Madrid, SpainDepartment of Conservative Dentistry and Buccofacial Prostheses, School of Dentistry, Complutense University of Madrid, 28040 Madrid, SpainDepartment of Conservative Dentistry and Buccofacial Prostheses, School of Dentistry, Complutense University of Madrid, 28040 Madrid, SpainDepartment of Reconstructive Dentistry and Gerodontology, School of Dental Medicine, University of Bern, 3010 Bern, SwitzerlandDepartment of Dental Clinical Specialties, School of Dentistry, Complutense University of Madrid, 28040 Madrid, SpainDepartment of Conservative Dentistry and Buccofacial Prostheses, School of Dentistry, Complutense University of Madrid, 28040 Madrid, SpainThe hydrolysis of the collagen matrix by metalloproteinases (MMPs) is one of the paradigms that currently arouses most interest due to its close relationship with a decrease in bond strength (BS) and consequent restoration failure. Chlorhexidine 2% has demonstrated its ability to inhibit MMPs’ activity in the permanent dentition, improving the duration of resin–dentine, but there are few studies on deciduous dentition and its possible repercussions. Aim: To determine the influence of 2% chlorhexidine digluconate (CHX) as a dentine pretreatment on the BS of three adhesive systems on primary molars. Methods: 128 primary extracted molars were assigned to eight groups at random. BS in vitro was recorded by micropush-out test, and analyzed by two-way ANOVA. Results: BS values oscillated from 15.01 MPa to 20.41 MPa. There was no statistically relevant variation between the BS total mean of those adhesive groups that had received CHX pretreatment versus those that did not. Adper Prompt L-Pop was the self-etching adhesive with the best BS. Adper Scotchbond 1XT was the total-etch adhesive with the best BS values. Conclusions: Application of 2% chlorhexidine for 60 s as dentine pretreatment did not affect the immediate BS of several adhesive systems used in primary dentition.https://www.mdpi.com/2076-3417/12/6/2964primary teethmetalloproteinasesdentin bonding agentschlorhexidine digluconatedentistrycomposite
spellingShingle Laura Velayos-Galán
Pedro Molinero-Mourelle
Pablo Sevilla
Manrique Fonseca
María Rosa Mourelle-Martínez
Vicente Vera-González
Influence of 2% Chlorhexidine on the Bond Strength of Three Adhesive Systems on Primary Molars: An In Vitro Study
Applied Sciences
primary teeth
metalloproteinases
dentin bonding agents
chlorhexidine digluconate
dentistry
composite
title Influence of 2% Chlorhexidine on the Bond Strength of Three Adhesive Systems on Primary Molars: An In Vitro Study
title_full Influence of 2% Chlorhexidine on the Bond Strength of Three Adhesive Systems on Primary Molars: An In Vitro Study
title_fullStr Influence of 2% Chlorhexidine on the Bond Strength of Three Adhesive Systems on Primary Molars: An In Vitro Study
title_full_unstemmed Influence of 2% Chlorhexidine on the Bond Strength of Three Adhesive Systems on Primary Molars: An In Vitro Study
title_short Influence of 2% Chlorhexidine on the Bond Strength of Three Adhesive Systems on Primary Molars: An In Vitro Study
title_sort influence of 2 chlorhexidine on the bond strength of three adhesive systems on primary molars an in vitro study
topic primary teeth
metalloproteinases
dentin bonding agents
chlorhexidine digluconate
dentistry
composite
url https://www.mdpi.com/2076-3417/12/6/2964
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