Multiple myeloma presenting as a cervical intraforaminal tumor: A case report and review of literature
Multiple myeloma (MM) is a hematological malignancy with characteristic clonal plasma cell proliferation and production of monoclonal immunoglobulins. Although it can often metastasize to the bony spine, completely extravertebral and extra-/intradural manifestations are exceedingly rare. In this cas...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Surgery |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2023.1011152/full |
| _version_ | 1828051238143393792 |
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| author | Dragan Jankovic Darius Kalasauskas Naureen Keric Malte Ottenhausen Florian Ringel |
| author_facet | Dragan Jankovic Darius Kalasauskas Naureen Keric Malte Ottenhausen Florian Ringel |
| author_sort | Dragan Jankovic |
| collection | DOAJ |
| description | Multiple myeloma (MM) is a hematological malignancy with characteristic clonal plasma cell proliferation and production of monoclonal immunoglobulins. Although it can often metastasize to the bony spine, completely extravertebral and extra-/intradural manifestations are exceedingly rare. In this case report, we describe a 51-year-old male patient with cervical extradural and intraforaminal MM who was surgically treated in our department. Clinical findings and radiological images were retrieved from medical records and an imaging system. This unusual localization of MM and similar cases in the literature are reviewed in detail. The patient underwent tumor resection via a ventral approach, and postoperative MRI demonstrated a sufficient decompression of neural structures. No new neurological deficits were observed at subsequent follow-ups. Although 7 cases of extramedullary extradural manifestations of multiple myeloma have been described in the literature so far, this is the first case of intraforaminal extramedullary multiple myeloma located in the cervical spine and treated by surgery. |
| first_indexed | 2024-04-10T19:34:55Z |
| format | Article |
| id | doaj.art-cfde45b0a2d14267b9734b726f1fddfb |
| institution | Directory Open Access Journal |
| issn | 2296-875X |
| language | English |
| last_indexed | 2024-04-10T19:34:55Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Surgery |
| spelling | doaj.art-cfde45b0a2d14267b9734b726f1fddfb2023-01-30T08:52:15ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2023-01-011010.3389/fsurg.2023.10111521011152Multiple myeloma presenting as a cervical intraforaminal tumor: A case report and review of literatureDragan JankovicDarius KalasauskasNaureen KericMalte OttenhausenFlorian RingelMultiple myeloma (MM) is a hematological malignancy with characteristic clonal plasma cell proliferation and production of monoclonal immunoglobulins. Although it can often metastasize to the bony spine, completely extravertebral and extra-/intradural manifestations are exceedingly rare. In this case report, we describe a 51-year-old male patient with cervical extradural and intraforaminal MM who was surgically treated in our department. Clinical findings and radiological images were retrieved from medical records and an imaging system. This unusual localization of MM and similar cases in the literature are reviewed in detail. The patient underwent tumor resection via a ventral approach, and postoperative MRI demonstrated a sufficient decompression of neural structures. No new neurological deficits were observed at subsequent follow-ups. Although 7 cases of extramedullary extradural manifestations of multiple myeloma have been described in the literature so far, this is the first case of intraforaminal extramedullary multiple myeloma located in the cervical spine and treated by surgery.https://www.frontiersin.org/articles/10.3389/fsurg.2023.1011152/fullcase reportmultiple myelomaoutcomespinesurgery |
| spellingShingle | Dragan Jankovic Darius Kalasauskas Naureen Keric Malte Ottenhausen Florian Ringel Multiple myeloma presenting as a cervical intraforaminal tumor: A case report and review of literature Frontiers in Surgery case report multiple myeloma outcome spine surgery |
| title | Multiple myeloma presenting as a cervical intraforaminal tumor: A case report and review of literature |
| title_full | Multiple myeloma presenting as a cervical intraforaminal tumor: A case report and review of literature |
| title_fullStr | Multiple myeloma presenting as a cervical intraforaminal tumor: A case report and review of literature |
| title_full_unstemmed | Multiple myeloma presenting as a cervical intraforaminal tumor: A case report and review of literature |
| title_short | Multiple myeloma presenting as a cervical intraforaminal tumor: A case report and review of literature |
| title_sort | multiple myeloma presenting as a cervical intraforaminal tumor a case report and review of literature |
| topic | case report multiple myeloma outcome spine surgery |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2023.1011152/full |
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