Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease
Around 50 mycobacteria species cause human disease. Immunosuppressive states predispose to non-tuberculous mycobaterium infection, such as Mycobacterium chelonae: AFB, non-tuberculous, fast growth of low virulence and uncommon as a human pathogen. It may...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Dermatologia
2015-02-01
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| Series: | Anais Brasileiros de Dermatologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000100104&tlng=en |
| _version_ | 1830201170174410752 |
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| author | Renan Lage Danilo Guerreiro Zeolo Biccigo Felipe Borba Calixto Santos Erica Chimara Elisangela Samartin Pegas Pereira Adilson da Costa |
| author_facet | Renan Lage Danilo Guerreiro Zeolo Biccigo Felipe Borba Calixto Santos Erica Chimara Elisangela Samartin Pegas Pereira Adilson da Costa |
| author_sort | Renan Lage |
| collection | DOAJ |
| description | Around 50 mycobacteria species cause human disease. Immunosuppressive states predispose to non-tuberculous mycobaterium infection, such as Mycobacterium chelonae: AFB, non-tuberculous, fast growth of low virulence and uncommon as a human pathogen. It may compromise the skin and soft tissues, lungs, lymph nodes and there is also a disseminated presentation. The diagnosis involves AFB identification and culture on Agar and Lowenstein-Jensen medium base. A 41-year-old female with MCTD (LES predominance) is reported, presenting painless nodules in the right forearm. She denied local trauma. Immunosuppressed with prednisone and cyclophosphamide for 24 months. Lesion biopsy has demonstrated positive bacilloscopy (Ziehl-Neelsen stain) and M.chelonae in culture (Lowenstein-Jensen medium base), therefore clarithromycin treatment has been started (best therapy choice in the literature). |
| first_indexed | 2024-12-18T02:47:51Z |
| format | Article |
| id | doaj.art-cfdfffbc56494e458e53150fb58374f4 |
| institution | Directory Open Access Journal |
| issn | 0365-0596 |
| language | English |
| last_indexed | 2024-12-18T02:47:51Z |
| publishDate | 2015-02-01 |
| publisher | Sociedade Brasileira de Dermatologia |
| record_format | Article |
| series | Anais Brasileiros de Dermatologia |
| spelling | doaj.art-cfdfffbc56494e458e53150fb58374f42022-12-21T21:23:31ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05962015-02-0190110410710.1590/abd1806-4841.20152276Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue diseaseRenan LageDanilo Guerreiro Zeolo BiccigoFelipe Borba Calixto SantosErica ChimaraElisangela Samartin Pegas PereiraAdilson da CostaAround 50 mycobacteria species cause human disease. Immunosuppressive states predispose to non-tuberculous mycobaterium infection, such as Mycobacterium chelonae: AFB, non-tuberculous, fast growth of low virulence and uncommon as a human pathogen. It may compromise the skin and soft tissues, lungs, lymph nodes and there is also a disseminated presentation. The diagnosis involves AFB identification and culture on Agar and Lowenstein-Jensen medium base. A 41-year-old female with MCTD (LES predominance) is reported, presenting painless nodules in the right forearm. She denied local trauma. Immunosuppressed with prednisone and cyclophosphamide for 24 months. Lesion biopsy has demonstrated positive bacilloscopy (Ziehl-Neelsen stain) and M.chelonae in culture (Lowenstein-Jensen medium base), therefore clarithromycin treatment has been started (best therapy choice in the literature).http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000100104&tlng=enClarithromycinImmunosuppressionMixed connective tissue diseaseMycobacterium chelonaeMycobacterium fortuitumNontuberculous mycobacteriaPrednisoneSkinVirulence |
| spellingShingle | Renan Lage Danilo Guerreiro Zeolo Biccigo Felipe Borba Calixto Santos Erica Chimara Elisangela Samartin Pegas Pereira Adilson da Costa Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease Anais Brasileiros de Dermatologia Clarithromycin Immunosuppression Mixed connective tissue disease Mycobacterium chelonae Mycobacterium fortuitum Nontuberculous mycobacteria Prednisone Skin Virulence |
| title | Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease |
| title_full | Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease |
| title_fullStr | Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease |
| title_full_unstemmed | Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease |
| title_short | Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease |
| title_sort | mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease |
| topic | Clarithromycin Immunosuppression Mixed connective tissue disease Mycobacterium chelonae Mycobacterium fortuitum Nontuberculous mycobacteria Prednisone Skin Virulence |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000100104&tlng=en |
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