Brain Injury Associated with Chronic Spontaneous Urticaria: a Kounis-Like Syndrome?
‘Kounis Syndrome’ is an acute coronary artery event due to an artery spasm occurring during immediate hypersensi- tivity reactions or chronic spontaneous urticaria. Recently it has been reported in other systems, including the cerebral vasculature. We present a case series of three patients observed...
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| Format: | Article |
| Language: | English |
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Sociedade Portuguesa de Dermatologia e Venereologia
2020-01-01
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| Series: | Revista da Sociedade Portuguesa de Dermatologia e Venereologia |
| Subjects: | |
| Online Access: | https://revista.spdv.com.pt/index.php/spdv/article/view/1131 |
| _version_ | 1811311941926256640 |
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| author | Luis Santiago Margarida Gonçalo |
| author_facet | Luis Santiago Margarida Gonçalo |
| author_sort | Luis Santiago |
| collection | DOAJ |
| description | ‘Kounis Syndrome’ is an acute coronary artery event due to an artery spasm occurring during immediate hypersensi- tivity reactions or chronic spontaneous urticaria. Recently it has been reported in other systems, including the cerebral vasculature. We present a case series of three patients observed between January 2016 and December 2018 with acute and transient brain injury associated with concomitant exacerbation of chronic spontaneous urticaria, including one patient with multiple recurrences of neurologic symptoms during exacerbations of urticaria. Minor imaging defects were observed in two patients, but there were no apparent vascular risk factors or coagulation abnormalities that might explain neurologic symptoms.
Chronic spontaneous urticaria, through activation of mast cells and mediator release, seems capable of inducing cerebral arterial aggression. The authors want to call the attention to this possible association, reinforcing the need to keep urticaria under control to prevent neurological manifestations. |
| first_indexed | 2024-04-13T10:27:49Z |
| format | Article |
| id | doaj.art-cfe42b0695284070a0239ec604bd35e6 |
| institution | Directory Open Access Journal |
| issn | 2182-2395 2182-2409 |
| language | English |
| last_indexed | 2024-04-13T10:27:49Z |
| publishDate | 2020-01-01 |
| publisher | Sociedade Portuguesa de Dermatologia e Venereologia |
| record_format | Article |
| series | Revista da Sociedade Portuguesa de Dermatologia e Venereologia |
| spelling | doaj.art-cfe42b0695284070a0239ec604bd35e62022-12-22T02:50:17ZengSociedade Portuguesa de Dermatologia e VenereologiaRevista da Sociedade Portuguesa de Dermatologia e Venereologia2182-23952182-24092020-01-0177410.29021/spdv.77.4.1131Brain Injury Associated with Chronic Spontaneous Urticaria: a Kounis-Like Syndrome?Luis Santiago0Margarida Gonçalo1Dermatology Department, Coimbra University Hospital, Coimbra, PortugalDermatology Department, Coimbra University Hospital, Coimbra, Portugal; Faculty of Medicine, University of Coimbra, Coimbra, Portugal‘Kounis Syndrome’ is an acute coronary artery event due to an artery spasm occurring during immediate hypersensi- tivity reactions or chronic spontaneous urticaria. Recently it has been reported in other systems, including the cerebral vasculature. We present a case series of three patients observed between January 2016 and December 2018 with acute and transient brain injury associated with concomitant exacerbation of chronic spontaneous urticaria, including one patient with multiple recurrences of neurologic symptoms during exacerbations of urticaria. Minor imaging defects were observed in two patients, but there were no apparent vascular risk factors or coagulation abnormalities that might explain neurologic symptoms. Chronic spontaneous urticaria, through activation of mast cells and mediator release, seems capable of inducing cerebral arterial aggression. The authors want to call the attention to this possible association, reinforcing the need to keep urticaria under control to prevent neurological manifestations.https://revista.spdv.com.pt/index.php/spdv/article/view/1131urticariachronic spontaneous urticariabrain injuryKounis Syndrome |
| spellingShingle | Luis Santiago Margarida Gonçalo Brain Injury Associated with Chronic Spontaneous Urticaria: a Kounis-Like Syndrome? Revista da Sociedade Portuguesa de Dermatologia e Venereologia urticaria chronic spontaneous urticaria brain injury Kounis Syndrome |
| title | Brain Injury Associated with Chronic Spontaneous Urticaria: a Kounis-Like Syndrome? |
| title_full | Brain Injury Associated with Chronic Spontaneous Urticaria: a Kounis-Like Syndrome? |
| title_fullStr | Brain Injury Associated with Chronic Spontaneous Urticaria: a Kounis-Like Syndrome? |
| title_full_unstemmed | Brain Injury Associated with Chronic Spontaneous Urticaria: a Kounis-Like Syndrome? |
| title_short | Brain Injury Associated with Chronic Spontaneous Urticaria: a Kounis-Like Syndrome? |
| title_sort | brain injury associated with chronic spontaneous urticaria a kounis like syndrome |
| topic | urticaria chronic spontaneous urticaria brain injury Kounis Syndrome |
| url | https://revista.spdv.com.pt/index.php/spdv/article/view/1131 |
| work_keys_str_mv | AT luissantiago braininjuryassociatedwithchronicspontaneousurticariaakounislikesyndrome AT margaridagoncalo braininjuryassociatedwithchronicspontaneousurticariaakounislikesyndrome |