The role of proline rich tyrosine kinase 2 (Pyk2) on cisplatin resistance in hepatocellular carcinoma.

AIMS: We previously demonstrated Proline rich tyrosine kinase 2 (Pyk2) plays important roles in regulating tumor progression, migration and invasion in hepatocellular carcinoma (HCC). In this study, we aimed to examine the role of proline rich tyrosine kinase 2 (Pyk2) on cisplatin resistance in HCC...

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Autors principals: Wei Geng, Kevin T P Ng, Chris K W Sun, Wing Lung Yau, Xiao Bing Liu, Qiao Cheng, Ronnie T P Poon, Chung Mau Lo, Kwan Man, Sheung Tat Fan
Format: Article
Idioma:English
Publicat: Public Library of Science (PLoS) 2011-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC3212555?pdf=render