Diagnostic Performance of Diffusion-Weighted MRI and FDG PET/CT for Detecting the Local Recurrence of Head and Neck Squamous Cell Carcinoma
Objective: To compare the efficacy between diffusion-weighted magnetic resonance imaging (DW-MRI) and positron emission tomography/computed tomography (PET/CT) in detecting the local recurrence of head and neck squamous cell carcinoma (HNSCC) following treatment in the same patient group.Methods: Tw...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2016-06-01
|
| Series: | İstanbul Medical Journal |
| Subjects: | |
| Online Access: |
http://imj.galenos.com.tr/archives/archive-detail/article-preview/diagnostic-performance-of-diffusion-weighted-mr-an/20855
|
| _version_ | 1797910611818971136 |
|---|---|
| author | İbrahim İlker Öz İsmail Şerifoğlu Yavuz Sami Salihoğlu Murat Damar Aykut Erdem Dinç Rabiye Uslu Mustafa Çağatay Büyükuysal Oktay Erdem |
| author_facet | İbrahim İlker Öz İsmail Şerifoğlu Yavuz Sami Salihoğlu Murat Damar Aykut Erdem Dinç Rabiye Uslu Mustafa Çağatay Büyükuysal Oktay Erdem |
| author_sort | İbrahim İlker Öz |
| collection | DOAJ |
| description | Objective: To compare the efficacy between diffusion-weighted magnetic resonance imaging (DW-MRI) and positron emission tomography/computed tomography (PET/CT) in detecting the local recurrence of head and neck squamous cell carcinoma (HNSCC) following treatment in the same patient group.Methods: Twenty-three patients who had biopsy-proven HNSCC were enrolled. All patients were treated with radiotherapy and followed up with MRI and PET/CT. The median delay times between radiotherapy and MRI and between MRI and FDG PET/CT were 71 days (range: 43–98 days) and 75 days (range: 44–103 days), respectively. Diffusion-weighted single-shot echo planar imaging was performed before contrast injection at b values of 0 and 1000 s/ mm2. PET/CT images were acquired after the administration of 3.7 MBq/kg of fluorine-18-fluorodeoxyglucose, and the images were acquired 1 h later.Results: The apparent diffusion coefficient (ADC)mean values of the recurrence group were significantly lower than those of the post-treatment changes group (0.773 vs. 1.588×10−3 mm2/s, respectively; p<0.001). The standardized uptake value (SUV)max values of the recurrence group were significantly higher than those of the post-treatment changes group (15.642 vs. 4.508, respectively; p<0.001). There was no significant correlation between ADCmean and SUVmax values of recurrence (r=0.341; p=0.278), whereas there was a negative correlation between ADCmean and SUVmax values of the post-treatment changes (r=−0.691; p=0.019).Conclusion: PET/CT and DW-MRI are effective methods for distinguishing recurrence from post-treatment changes. Follow-up should begin with DW-MRI, and in patients with a suspicion of recurrence, PET-CT should be added to the follow-up protocol. |
| first_indexed | 2024-04-10T11:27:02Z |
| format | Article |
| id | doaj.art-cfe4a21ae02b4f08a223af67faa58a52 |
| institution | Directory Open Access Journal |
| issn | 2619-9793 2148-094X |
| language | English |
| last_indexed | 2024-04-10T11:27:02Z |
| publishDate | 2016-06-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | İstanbul Medical Journal |
| spelling | doaj.art-cfe4a21ae02b4f08a223af67faa58a522023-02-15T16:18:22ZengGalenos Yayineviİstanbul Medical Journal2619-97932148-094X2016-06-01172485310.5152/imj.2016.1501013049054Diagnostic Performance of Diffusion-Weighted MRI and FDG PET/CT for Detecting the Local Recurrence of Head and Neck Squamous Cell Carcinomaİbrahim İlker Öz0İsmail Şerifoğlu1Yavuz Sami Salihoğlu2Murat Damar3Aykut Erdem Dinç4Rabiye Uslu5Mustafa Çağatay Büyükuysal6Oktay Erdem7 Department of Radiology, Bülent Ecevit University School of Medicine, Zonguldak, Türkiye Department of Radiology, Bülent Ecevit University School of Medicine, Zonguldak, Türkiye Department of Nuclear Medicine, Bülent Ecevit University School of Medicine, Zonguldak, Türkiye Department of Otolaryngology, Bülent Ecevit University School of Medicine, Zonguldak, Türkiye Department of Otolaryngology, Bülent Ecevit University School of Medicine, Zonguldak, Türkiye Department of Nuclear Medicine, Bülent Ecevit University School of Medicine, Zonguldak, Türkiye Department of Medical Statistics, Bülent Ecevit University School of Medicine, Zonguldak, Türkiye Department of Radiology, Bülent Ecevit University School of Medicine, Zonguldak, Türkiye Objective: To compare the efficacy between diffusion-weighted magnetic resonance imaging (DW-MRI) and positron emission tomography/computed tomography (PET/CT) in detecting the local recurrence of head and neck squamous cell carcinoma (HNSCC) following treatment in the same patient group.Methods: Twenty-three patients who had biopsy-proven HNSCC were enrolled. All patients were treated with radiotherapy and followed up with MRI and PET/CT. The median delay times between radiotherapy and MRI and between MRI and FDG PET/CT were 71 days (range: 43–98 days) and 75 days (range: 44–103 days), respectively. Diffusion-weighted single-shot echo planar imaging was performed before contrast injection at b values of 0 and 1000 s/ mm2. PET/CT images were acquired after the administration of 3.7 MBq/kg of fluorine-18-fluorodeoxyglucose, and the images were acquired 1 h later.Results: The apparent diffusion coefficient (ADC)mean values of the recurrence group were significantly lower than those of the post-treatment changes group (0.773 vs. 1.588×10−3 mm2/s, respectively; p<0.001). The standardized uptake value (SUV)max values of the recurrence group were significantly higher than those of the post-treatment changes group (15.642 vs. 4.508, respectively; p<0.001). There was no significant correlation between ADCmean and SUVmax values of recurrence (r=0.341; p=0.278), whereas there was a negative correlation between ADCmean and SUVmax values of the post-treatment changes (r=−0.691; p=0.019).Conclusion: PET/CT and DW-MRI are effective methods for distinguishing recurrence from post-treatment changes. Follow-up should begin with DW-MRI, and in patients with a suspicion of recurrence, PET-CT should be added to the follow-up protocol. http://imj.galenos.com.tr/archives/archive-detail/article-preview/diagnostic-performance-of-diffusion-weighted-mr-an/20855 Head and neck cancerdiffusion weighted imagingapparent diffusion coefficientpositron emission tomography/computed tomographystandardized uptake value |
| spellingShingle | İbrahim İlker Öz İsmail Şerifoğlu Yavuz Sami Salihoğlu Murat Damar Aykut Erdem Dinç Rabiye Uslu Mustafa Çağatay Büyükuysal Oktay Erdem Diagnostic Performance of Diffusion-Weighted MRI and FDG PET/CT for Detecting the Local Recurrence of Head and Neck Squamous Cell Carcinoma İstanbul Medical Journal Head and neck cancer diffusion weighted imaging apparent diffusion coefficient positron emission tomography/computed tomography standardized uptake value |
| title | Diagnostic Performance of Diffusion-Weighted MRI and FDG PET/CT for Detecting the Local Recurrence of Head and Neck Squamous Cell Carcinoma |
| title_full | Diagnostic Performance of Diffusion-Weighted MRI and FDG PET/CT for Detecting the Local Recurrence of Head and Neck Squamous Cell Carcinoma |
| title_fullStr | Diagnostic Performance of Diffusion-Weighted MRI and FDG PET/CT for Detecting the Local Recurrence of Head and Neck Squamous Cell Carcinoma |
| title_full_unstemmed | Diagnostic Performance of Diffusion-Weighted MRI and FDG PET/CT for Detecting the Local Recurrence of Head and Neck Squamous Cell Carcinoma |
| title_short | Diagnostic Performance of Diffusion-Weighted MRI and FDG PET/CT for Detecting the Local Recurrence of Head and Neck Squamous Cell Carcinoma |
| title_sort | diagnostic performance of diffusion weighted mri and fdg pet ct for detecting the local recurrence of head and neck squamous cell carcinoma |
| topic | Head and neck cancer diffusion weighted imaging apparent diffusion coefficient positron emission tomography/computed tomography standardized uptake value |
| url |
http://imj.galenos.com.tr/archives/archive-detail/article-preview/diagnostic-performance-of-diffusion-weighted-mr-an/20855
|
| work_keys_str_mv | AT ibrahimilkeroz diagnosticperformanceofdiffusionweightedmriandfdgpetctfordetectingthelocalrecurrenceofheadandnecksquamouscellcarcinoma AT ismailserifoglu diagnosticperformanceofdiffusionweightedmriandfdgpetctfordetectingthelocalrecurrenceofheadandnecksquamouscellcarcinoma AT yavuzsamisalihoglu diagnosticperformanceofdiffusionweightedmriandfdgpetctfordetectingthelocalrecurrenceofheadandnecksquamouscellcarcinoma AT muratdamar diagnosticperformanceofdiffusionweightedmriandfdgpetctfordetectingthelocalrecurrenceofheadandnecksquamouscellcarcinoma AT aykuterdemdinc diagnosticperformanceofdiffusionweightedmriandfdgpetctfordetectingthelocalrecurrenceofheadandnecksquamouscellcarcinoma AT rabiyeuslu diagnosticperformanceofdiffusionweightedmriandfdgpetctfordetectingthelocalrecurrenceofheadandnecksquamouscellcarcinoma AT mustafacagataybuyukuysal diagnosticperformanceofdiffusionweightedmriandfdgpetctfordetectingthelocalrecurrenceofheadandnecksquamouscellcarcinoma AT oktayerdem diagnosticperformanceofdiffusionweightedmriandfdgpetctfordetectingthelocalrecurrenceofheadandnecksquamouscellcarcinoma |