Splenic marginal zone lymphoma: a case report and literature review
Abstract Background Splenic marginal zone lymphoma (SMZL) is a rare non-Hodgkin lymphoma, and much little is known about its clinical characteristics and management strategies. Here we present a case of SMZL and review relevant literature to provide a better recognition of this disease entity. Case...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2020-10-01
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| Series: | World Journal of Surgical Oncology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12957-020-02030-3 |
| _version_ | 1818334815373492224 |
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| author | Shiyu Zhang Zefeng Xuan Liang Zhang Jiahua Lu Penghong Song Shusen Zheng |
| author_facet | Shiyu Zhang Zefeng Xuan Liang Zhang Jiahua Lu Penghong Song Shusen Zheng |
| author_sort | Shiyu Zhang |
| collection | DOAJ |
| description | Abstract Background Splenic marginal zone lymphoma (SMZL) is a rare non-Hodgkin lymphoma, and much little is known about its clinical characteristics and management strategies. Here we present a case of SMZL and review relevant literature to provide a better recognition of this disease entity. Case presentation A 49-year-old Chinese female was admitted to our hospital with complaints of abdominal distension and acid reflux. Physical examinations and imaging investigations suggested the presence of splenomegaly. Laboratory workups revealed mildly reduced white blood cell count otherwise was not remarkable. The patient underwent splenectomy. Histological examination combined with immunohistochemical analysis of the resected spleen confirmed the diagnosis of SMZL. The patient recovered uneventfully during follow-ups. Conclusions Due to the rarity and unspecific clinical features, SMZL is extremely challenging to be diagnosed preoperatively. Patients with SMZL are generally associated with favorable prognosis. Combining the staging characteristics of non-Hodgkin’s lymphoma and splenic primary lymphoma may assist in clinical staging management of SMZL. |
| first_indexed | 2024-12-13T14:13:32Z |
| format | Article |
| id | doaj.art-cfe78489fb3c4a2f983e109e21968266 |
| institution | Directory Open Access Journal |
| issn | 1477-7819 |
| language | English |
| last_indexed | 2024-12-13T14:13:32Z |
| publishDate | 2020-10-01 |
| publisher | BMC |
| record_format | Article |
| series | World Journal of Surgical Oncology |
| spelling | doaj.art-cfe78489fb3c4a2f983e109e219682662022-12-21T23:42:23ZengBMCWorld Journal of Surgical Oncology1477-78192020-10-011811710.1186/s12957-020-02030-3Splenic marginal zone lymphoma: a case report and literature reviewShiyu Zhang0Zefeng Xuan1Liang Zhang2Jiahua Lu3Penghong Song4Shusen Zheng5The First Affiliated Hospital, Zhejiang University School of Medicine, Division of Hepatobiliary and Pancreatic Surgery, Department of SurgeryThe First Affiliated Hospital, Zhejiang University School of Medicine, Division of Hepatobiliary and Pancreatic Surgery, Department of SurgeryThe First Affiliated Hospital, Zhejiang University School of Medicine, Division of Hepatobiliary and Pancreatic Surgery, Department of SurgeryThe First Affiliated Hospital, Zhejiang University School of Medicine, Division of Hepatobiliary and Pancreatic Surgery, Department of SurgeryThe First Affiliated Hospital, Zhejiang University School of Medicine, Division of Hepatobiliary and Pancreatic Surgery, Department of SurgeryThe First Affiliated Hospital, Zhejiang University School of Medicine, Division of Hepatobiliary and Pancreatic Surgery, Department of SurgeryAbstract Background Splenic marginal zone lymphoma (SMZL) is a rare non-Hodgkin lymphoma, and much little is known about its clinical characteristics and management strategies. Here we present a case of SMZL and review relevant literature to provide a better recognition of this disease entity. Case presentation A 49-year-old Chinese female was admitted to our hospital with complaints of abdominal distension and acid reflux. Physical examinations and imaging investigations suggested the presence of splenomegaly. Laboratory workups revealed mildly reduced white blood cell count otherwise was not remarkable. The patient underwent splenectomy. Histological examination combined with immunohistochemical analysis of the resected spleen confirmed the diagnosis of SMZL. The patient recovered uneventfully during follow-ups. Conclusions Due to the rarity and unspecific clinical features, SMZL is extremely challenging to be diagnosed preoperatively. Patients with SMZL are generally associated with favorable prognosis. Combining the staging characteristics of non-Hodgkin’s lymphoma and splenic primary lymphoma may assist in clinical staging management of SMZL.http://link.springer.com/article/10.1186/s12957-020-02030-3Splenic marginal zone lymphomaManagementStagingCase report |
| spellingShingle | Shiyu Zhang Zefeng Xuan Liang Zhang Jiahua Lu Penghong Song Shusen Zheng Splenic marginal zone lymphoma: a case report and literature review World Journal of Surgical Oncology Splenic marginal zone lymphoma Management Staging Case report |
| title | Splenic marginal zone lymphoma: a case report and literature review |
| title_full | Splenic marginal zone lymphoma: a case report and literature review |
| title_fullStr | Splenic marginal zone lymphoma: a case report and literature review |
| title_full_unstemmed | Splenic marginal zone lymphoma: a case report and literature review |
| title_short | Splenic marginal zone lymphoma: a case report and literature review |
| title_sort | splenic marginal zone lymphoma a case report and literature review |
| topic | Splenic marginal zone lymphoma Management Staging Case report |
| url | http://link.springer.com/article/10.1186/s12957-020-02030-3 |
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