Thyroid tissue in cervical lymph nodes, not always malignant

Abstract Thyroid tissue in cervical lymph nodes is an interesting and rare phenomenon that cannot be directly explained by embryology. Distinguishing malignant from benign thyroid tissue in cervical lymph nodes can be challenging but is essential for treatment and might have legal implications. Pati...

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Main Authors: Anton Frans Gijsen, Kirstin Marie Jeanne De Bruijn, Walter Mastboom
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.6261
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author Anton Frans Gijsen
Kirstin Marie Jeanne De Bruijn
Walter Mastboom
author_facet Anton Frans Gijsen
Kirstin Marie Jeanne De Bruijn
Walter Mastboom
author_sort Anton Frans Gijsen
collection DOAJ
description Abstract Thyroid tissue in cervical lymph nodes is an interesting and rare phenomenon that cannot be directly explained by embryology. Distinguishing malignant from benign thyroid tissue in cervical lymph nodes can be challenging but is essential for treatment and might have legal implications. Patients with incidentally found thyroid tissue in cervical lymph nodes during thyroid surgery were retrospectively identified. Clinical data and findings on pathology were retrospectively collected. Two patients with thyroid tissue in cervical lymph nodes were identified. Conventional pathology complemented with immunohistochemistry and molecular diagnostics showed the thyroid tissue in cervical lymph nodes to be benign. We show that benign thyroid tissue in cervical lymph nodes can be found in the absence or presence of a primary thyroid malignancy. A conservative approach is recommended if pathology shows benign thyroid tissue in cervical lymph nodes.
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spelling doaj.art-cfeab82e572b4720bac0e0c8fecc120e2022-12-22T03:21:58ZengWileyClinical Case Reports2050-09042022-09-01109n/an/a10.1002/ccr3.6261Thyroid tissue in cervical lymph nodes, not always malignantAnton Frans Gijsen0Kirstin Marie Jeanne De Bruijn1Walter Mastboom2Department of Surgery Medisch Spectrum Twente Enschede The NetherlandsDepartment of Surgery Medisch Spectrum Twente Enschede The NetherlandsDepartment of Surgery Medisch Spectrum Twente Enschede The NetherlandsAbstract Thyroid tissue in cervical lymph nodes is an interesting and rare phenomenon that cannot be directly explained by embryology. Distinguishing malignant from benign thyroid tissue in cervical lymph nodes can be challenging but is essential for treatment and might have legal implications. Patients with incidentally found thyroid tissue in cervical lymph nodes during thyroid surgery were retrospectively identified. Clinical data and findings on pathology were retrospectively collected. Two patients with thyroid tissue in cervical lymph nodes were identified. Conventional pathology complemented with immunohistochemistry and molecular diagnostics showed the thyroid tissue in cervical lymph nodes to be benign. We show that benign thyroid tissue in cervical lymph nodes can be found in the absence or presence of a primary thyroid malignancy. A conservative approach is recommended if pathology shows benign thyroid tissue in cervical lymph nodes.https://doi.org/10.1002/ccr3.6261thyroid surgerythyroid tissue in cervical lymph nodes
spellingShingle Anton Frans Gijsen
Kirstin Marie Jeanne De Bruijn
Walter Mastboom
Thyroid tissue in cervical lymph nodes, not always malignant
Clinical Case Reports
thyroid surgery
thyroid tissue in cervical lymph nodes
title Thyroid tissue in cervical lymph nodes, not always malignant
title_full Thyroid tissue in cervical lymph nodes, not always malignant
title_fullStr Thyroid tissue in cervical lymph nodes, not always malignant
title_full_unstemmed Thyroid tissue in cervical lymph nodes, not always malignant
title_short Thyroid tissue in cervical lymph nodes, not always malignant
title_sort thyroid tissue in cervical lymph nodes not always malignant
topic thyroid surgery
thyroid tissue in cervical lymph nodes
url https://doi.org/10.1002/ccr3.6261
work_keys_str_mv AT antonfransgijsen thyroidtissueincervicallymphnodesnotalwaysmalignant
AT kirstinmariejeannedebruijn thyroidtissueincervicallymphnodesnotalwaysmalignant
AT waltermastboom thyroidtissueincervicallymphnodesnotalwaysmalignant