Enhancement of Antiviral T-Cell Responses by Vitamin C Suggests New Strategies to Improve Manufacturing of Virus-Specific T Cells for Adoptive Immunotherapy

Enhancement of Antiviral T-Cell Responses by Vitamin C Suggests New Strategies to Improve Manufacturing of Virus-Specific T Cells for Adoptive Immunotherapy

Allogeneic and autologous transplantation of hematopoietic stem cells (HSCT) are being routinely used to treat patients with leukemia and lymphoma. Due to the required immunosuppression after stem cell transplantation, infection and reactivation by viruses are life-threatening complications. In rece...

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Bibliographic Details
Main Authors: Miriam Laubert, Agnes Bonifacius, Anna Christina Dragon, Caroline Mangare, Rainer Blasczyk, Jochen Huehn, Britta Eiz-Vesper
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Biology
Subjects:
T cells
antiviral immunity
cytomegalovirus
vitamin C
hematopoietic stem cell transplantation
cancer therapy
Online Access:https://www.mdpi.com/2079-7737/11/4/536

Internet

https://www.mdpi.com/2079-7737/11/4/536

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