Prevalence by health areas of chronic kidney disease in the diabetic population of Extremadura in 2012, 2013 and 2014. An observational study
Background and objective: Diabetes mellitus is the leading cause of chronic kidney disease (CKD) in our country. The objective was to estimate the global prevalence and by health areas of CKD in the diabetic population of Extremadura. Methods: Observational, longitudinal retrospective study in the d...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-11-01
|
| Series: | Nefrología (English Edition) |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2013251423000391 |
| _version_ | 1827980022317580288 |
|---|---|
| author | Leandro Fernández-Fernández Javier Goujat-Salas Carmen Ceballos-Malagón Manuel Tejero-Mas Francisco Luis Pérez-Caballero Francisco Buitrago-Ramírez |
| author_facet | Leandro Fernández-Fernández Javier Goujat-Salas Carmen Ceballos-Malagón Manuel Tejero-Mas Francisco Luis Pérez-Caballero Francisco Buitrago-Ramírez |
| author_sort | Leandro Fernández-Fernández |
| collection | DOAJ |
| description | Background and objective: Diabetes mellitus is the leading cause of chronic kidney disease (CKD) in our country. The objective was to estimate the global prevalence and by health areas of CKD in the diabetic population of Extremadura. Methods: Observational, longitudinal retrospective study in the diabetic population attended in the Extremadura Health System in 2012−2014. A total of 90,709 patients ≥18 years old were studied. The estimated glomerular filtration rate (eGFR) was calculated using the Chronic Kidney Disease Epidemiology Collaboration equation (CKD-EPI). The presence of CKD was was defined as follows: an eGFR <60 ml/min/1.73 m2 in a time period ≥ of three months or the presence of renal damage, as evaluated by an urine albumin-creatinine ratio (UACR) ≥30 mg/g, with or without reduced eGFR, also in a time period ≥ of three months. Results: The overall prevalence of CKD was 15.6% (17.5% in women and 13.7% in men) and it was higher in the province of Cáceres (17.0%) than in Badajoz (14.8%, p < 0.001), with the lowest prevalence in the Navalmoral de la Mata health area (13.0%) and the highest in Plasencia (17.8%, p < 0.001). The prevalence of CKD defined without the need for confirmation of the sustainability of kidney damage or decreased eGFR was 26.1% (29.3% in women and 22.9% in men), which represents an overestimation of the prevalence of 67%. Conclusions: The prevalence of CKD in Extremadura's diabetic population is lower than usually referred to and differs significantly between its health areas. Resumen: Antecedentes y objetivo: La diabetes mellitus es la principal causa de enfermedad renal crónica (ERC) en nuestro país. El objetivo fue estimar la prevalencia global y por áreas sanitarias de ERC en la población diabética de Extremadura. Pacientes y métodos: Estudio observacional, longitudinal, retrospectivo en la población diabética atendida en el Sistema Extremeño de Salud durante el período 2012−2014. Se incluyeron 90.709 pacientes ≥18 años. El cálculo del filtrado glomerular estimado (FGe) se realizó mediante la ecuación CKD-EPI (derivada de la ecuación desarrollada por la Chronic Kidney Disease Epidemiology Collaboration) y se calculó el cociente albumina/creatinina en orina (CAC). Se consideró paciente con ERC a todo aquel que en su última analítica tenía un FGe <60 mL/min/1.73 m2 y/o un CAC ≥ 30 mg/g, confirmados en una determinación previa separada al menos por 3 meses. Resultados: La prevalencia global de ERC fue del 15,6% (17,5% en mujeres y 13,7% en varones) y fue mayor en la provincia de Cáceres (17,0%) que en la de Badajoz (14,8%, p < 0,001), encontrándose la menor prevalencia en el área sanitaria de Navalmoral de la Mata (13,0%) y la mayor en la de Plasencia (17,8%, p < 0,001). La prevalencia de ERC definida sin necesidad de confirmación de la sostenibilidad del daño renal o del FGe disminuido fue del 26,1% (29,3% en mujeres y 22,9% en varones) lo que supone una sobreestimación de la prevalencia del 67%. Conclusiones: La prevalencia de ERC en población diabética extremeña es menor a la referida habitualmente y difiere significativamente entre sus áreas sanitarias. |
| first_indexed | 2024-04-09T21:46:01Z |
| format | Article |
| id | doaj.art-cfed69c9d5f644f6acf8b3b6a832d72d |
| institution | Directory Open Access Journal |
| issn | 2013-2514 |
| language | English |
| last_indexed | 2024-04-09T21:46:01Z |
| publishDate | 2022-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Nefrología (English Edition) |
| spelling | doaj.art-cfed69c9d5f644f6acf8b3b6a832d72d2023-03-25T05:10:38ZengElsevierNefrología (English Edition)2013-25142022-11-01426704713Prevalence by health areas of chronic kidney disease in the diabetic population of Extremadura in 2012, 2013 and 2014. An observational studyLeandro Fernández-Fernández0Javier Goujat-Salas1Carmen Ceballos-Malagón2Manuel Tejero-Mas3Francisco Luis Pérez-Caballero4Francisco Buitrago-Ramírez5Centro de Salud de Zafra, Servicio Extremeño de Salud, Zafra, Badajoz, SpainCentro de Salud Obispo Paulo (Urbano 3), Servicio Extremeño de Salud, Mérida, Badajoz, SpainCentro de Salud Obispo Paulo (Urbano 3), Servicio Extremeño de Salud, Mérida, Badajoz, SpainCentro de Salud de Don Benito Oeste, Servicio Extremeño de Salud, Don Benito, Badajoz, SpainHospital de Mérida, Servicio Extremeño de Salud, Mérida, Badajoz, SpainCentro de Salud Universitario “La Paz”, Servicio Extremeño de Salud, Facultad de Medicina, Universidad de Extremadura, Badajoz, Spain; Corresponding author.Background and objective: Diabetes mellitus is the leading cause of chronic kidney disease (CKD) in our country. The objective was to estimate the global prevalence and by health areas of CKD in the diabetic population of Extremadura. Methods: Observational, longitudinal retrospective study in the diabetic population attended in the Extremadura Health System in 2012−2014. A total of 90,709 patients ≥18 years old were studied. The estimated glomerular filtration rate (eGFR) was calculated using the Chronic Kidney Disease Epidemiology Collaboration equation (CKD-EPI). The presence of CKD was was defined as follows: an eGFR <60 ml/min/1.73 m2 in a time period ≥ of three months or the presence of renal damage, as evaluated by an urine albumin-creatinine ratio (UACR) ≥30 mg/g, with or without reduced eGFR, also in a time period ≥ of three months. Results: The overall prevalence of CKD was 15.6% (17.5% in women and 13.7% in men) and it was higher in the province of Cáceres (17.0%) than in Badajoz (14.8%, p < 0.001), with the lowest prevalence in the Navalmoral de la Mata health area (13.0%) and the highest in Plasencia (17.8%, p < 0.001). The prevalence of CKD defined without the need for confirmation of the sustainability of kidney damage or decreased eGFR was 26.1% (29.3% in women and 22.9% in men), which represents an overestimation of the prevalence of 67%. Conclusions: The prevalence of CKD in Extremadura's diabetic population is lower than usually referred to and differs significantly between its health areas. Resumen: Antecedentes y objetivo: La diabetes mellitus es la principal causa de enfermedad renal crónica (ERC) en nuestro país. El objetivo fue estimar la prevalencia global y por áreas sanitarias de ERC en la población diabética de Extremadura. Pacientes y métodos: Estudio observacional, longitudinal, retrospectivo en la población diabética atendida en el Sistema Extremeño de Salud durante el período 2012−2014. Se incluyeron 90.709 pacientes ≥18 años. El cálculo del filtrado glomerular estimado (FGe) se realizó mediante la ecuación CKD-EPI (derivada de la ecuación desarrollada por la Chronic Kidney Disease Epidemiology Collaboration) y se calculó el cociente albumina/creatinina en orina (CAC). Se consideró paciente con ERC a todo aquel que en su última analítica tenía un FGe <60 mL/min/1.73 m2 y/o un CAC ≥ 30 mg/g, confirmados en una determinación previa separada al menos por 3 meses. Resultados: La prevalencia global de ERC fue del 15,6% (17,5% en mujeres y 13,7% en varones) y fue mayor en la provincia de Cáceres (17,0%) que en la de Badajoz (14,8%, p < 0,001), encontrándose la menor prevalencia en el área sanitaria de Navalmoral de la Mata (13,0%) y la mayor en la de Plasencia (17,8%, p < 0,001). La prevalencia de ERC definida sin necesidad de confirmación de la sostenibilidad del daño renal o del FGe disminuido fue del 26,1% (29,3% en mujeres y 22,9% en varones) lo que supone una sobreestimación de la prevalencia del 67%. Conclusiones: La prevalencia de ERC en población diabética extremeña es menor a la referida habitualmente y difiere significativamente entre sus áreas sanitarias.http://www.sciencedirect.com/science/article/pii/S2013251423000391Enfermedad renal crónicaInsuficiencia renalAlbuminuriaDiabetes mellitusAtención primaria de salud |
| spellingShingle | Leandro Fernández-Fernández Javier Goujat-Salas Carmen Ceballos-Malagón Manuel Tejero-Mas Francisco Luis Pérez-Caballero Francisco Buitrago-Ramírez Prevalence by health areas of chronic kidney disease in the diabetic population of Extremadura in 2012, 2013 and 2014. An observational study Nefrología (English Edition) Enfermedad renal crónica Insuficiencia renal Albuminuria Diabetes mellitus Atención primaria de salud |
| title | Prevalence by health areas of chronic kidney disease in the diabetic population of Extremadura in 2012, 2013 and 2014. An observational study |
| title_full | Prevalence by health areas of chronic kidney disease in the diabetic population of Extremadura in 2012, 2013 and 2014. An observational study |
| title_fullStr | Prevalence by health areas of chronic kidney disease in the diabetic population of Extremadura in 2012, 2013 and 2014. An observational study |
| title_full_unstemmed | Prevalence by health areas of chronic kidney disease in the diabetic population of Extremadura in 2012, 2013 and 2014. An observational study |
| title_short | Prevalence by health areas of chronic kidney disease in the diabetic population of Extremadura in 2012, 2013 and 2014. An observational study |
| title_sort | prevalence by health areas of chronic kidney disease in the diabetic population of extremadura in 2012 2013 and 2014 an observational study |
| topic | Enfermedad renal crónica Insuficiencia renal Albuminuria Diabetes mellitus Atención primaria de salud |
| url | http://www.sciencedirect.com/science/article/pii/S2013251423000391 |
| work_keys_str_mv | AT leandrofernandezfernandez prevalencebyhealthareasofchronickidneydiseaseinthediabeticpopulationofextremadurain20122013and2014anobservationalstudy AT javiergoujatsalas prevalencebyhealthareasofchronickidneydiseaseinthediabeticpopulationofextremadurain20122013and2014anobservationalstudy AT carmenceballosmalagon prevalencebyhealthareasofchronickidneydiseaseinthediabeticpopulationofextremadurain20122013and2014anobservationalstudy AT manueltejeromas prevalencebyhealthareasofchronickidneydiseaseinthediabeticpopulationofextremadurain20122013and2014anobservationalstudy AT franciscoluisperezcaballero prevalencebyhealthareasofchronickidneydiseaseinthediabeticpopulationofextremadurain20122013and2014anobservationalstudy AT franciscobuitragoramirez prevalencebyhealthareasofchronickidneydiseaseinthediabeticpopulationofextremadurain20122013and2014anobservationalstudy |