Cognitive profile of patients with and without speech impairment in Parkinson's disease
ABSTRACT. Cognitive functions have been the subject of studies evaluating the pathophysiological mechanism of speech control. Objective: To compare the groups of patients with and without speech disorders with cognitive assessment, demographic, and clinical data (disease duration, functionality, an...
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| Format: | Article |
| Language: | English |
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Associação Neurologia Cognitiva e do Comportamento
2023-11-01
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| Series: | Dementia & Neuropsychologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642023000100324&lng=en&tlng=en |
| _version_ | 1827698584402788352 |
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| author | Nariana Mattos Figueiredo Sousa Juliana de Fátima Garcia Diniz Ana Paula Galvão Sonia Maria Dozzi Brucki |
| author_facet | Nariana Mattos Figueiredo Sousa Juliana de Fátima Garcia Diniz Ana Paula Galvão Sonia Maria Dozzi Brucki |
| author_sort | Nariana Mattos Figueiredo Sousa |
| collection | DOAJ |
| description | ABSTRACT. Cognitive functions have been the subject of studies evaluating the pathophysiological mechanism of speech control. Objective: To compare the groups of patients with and without speech disorders with cognitive assessment, demographic, and clinical data (disease duration, functionality, and motor symptoms). Methods: Retrospective, cross-sectional study. Patients were evaluated using the Addenbrooke's Cognitive Examination III and neuropsychological tests. The following speech subsystems were analyzed: articulation, phonation, resonance, and prosody, through auditory-perceptual evaluation (based on the Protocol for the Evaluation of Acquired Speech Disorders in Individuals with Parkinson's Disease — PADAF Protocol tests), observing aspects of speech programming and execution. The patients were distributed into three subgroups (normal cognition, mild cognitive impairment, and dementia). After speech evaluation, they were divided into two subgroups (with and without speech disorders). Results: A total of 150 patients participated in this study, 104 men and 46 women, 63.58 (8.81) years of age, 11.03 (4.00) years of schooling, 6.61 (4.69) years of disease progression, and with the highest proportion of individuals in stage I–II of the Hoehn & Yarh (H&Y) scale (86, or 57.33%). Statistically significant differences were observed between subgroups with and without speech alteration. Worse performance was verified in the Trail Making Test (TMT) TMT-Δ and a tendency of difference in the TMT-B of the subgroup with speech disorders, in addition to worse severity of motor symptoms (H&Y) and cognitive complaints. Conclusion: Individuals with speech disorders brought more frequent cognitive complaints and impairment below expected in tests assessing executive functions. Future studies, with stratification by type of speech disorder, are necessary to contribute to and validate these results. |
| first_indexed | 2024-03-10T13:33:19Z |
| format | Article |
| id | doaj.art-cfeddda1c3344845949f5e63623e8c49 |
| institution | Directory Open Access Journal |
| issn | 1980-5764 |
| language | English |
| last_indexed | 2024-03-10T13:33:19Z |
| publishDate | 2023-11-01 |
| publisher | Associação Neurologia Cognitiva e do Comportamento |
| record_format | Article |
| series | Dementia & Neuropsychologia |
| spelling | doaj.art-cfeddda1c3344845949f5e63623e8c492023-11-21T07:45:54ZengAssociação Neurologia Cognitiva e do ComportamentoDementia & Neuropsychologia1980-57642023-11-011710.1590/1980-5764-dn-2022-0093Cognitive profile of patients with and without speech impairment in Parkinson's diseaseNariana Mattos Figueiredo Sousahttps://orcid.org/0000-0001-7808-8020Juliana de Fátima Garcia Dinizhttps://orcid.org/0000-0002-4585-366XAna Paula Galvãohttps://orcid.org/0000-0001-7756-0821Sonia Maria Dozzi Bruckihttps://orcid.org/0000-0002-8303-6732ABSTRACT. Cognitive functions have been the subject of studies evaluating the pathophysiological mechanism of speech control. Objective: To compare the groups of patients with and without speech disorders with cognitive assessment, demographic, and clinical data (disease duration, functionality, and motor symptoms). Methods: Retrospective, cross-sectional study. Patients were evaluated using the Addenbrooke's Cognitive Examination III and neuropsychological tests. The following speech subsystems were analyzed: articulation, phonation, resonance, and prosody, through auditory-perceptual evaluation (based on the Protocol for the Evaluation of Acquired Speech Disorders in Individuals with Parkinson's Disease — PADAF Protocol tests), observing aspects of speech programming and execution. The patients were distributed into three subgroups (normal cognition, mild cognitive impairment, and dementia). After speech evaluation, they were divided into two subgroups (with and without speech disorders). Results: A total of 150 patients participated in this study, 104 men and 46 women, 63.58 (8.81) years of age, 11.03 (4.00) years of schooling, 6.61 (4.69) years of disease progression, and with the highest proportion of individuals in stage I–II of the Hoehn & Yarh (H&Y) scale (86, or 57.33%). Statistically significant differences were observed between subgroups with and without speech alteration. Worse performance was verified in the Trail Making Test (TMT) TMT-Δ and a tendency of difference in the TMT-B of the subgroup with speech disorders, in addition to worse severity of motor symptoms (H&Y) and cognitive complaints. Conclusion: Individuals with speech disorders brought more frequent cognitive complaints and impairment below expected in tests assessing executive functions. Future studies, with stratification by type of speech disorder, are necessary to contribute to and validate these results.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642023000100324&lng=en&tlng=enSpeech DisordersNeurocognitive DisordersNeuropsychological TestsAuditory PerceptionParkinson Disease |
| spellingShingle | Nariana Mattos Figueiredo Sousa Juliana de Fátima Garcia Diniz Ana Paula Galvão Sonia Maria Dozzi Brucki Cognitive profile of patients with and without speech impairment in Parkinson's disease Dementia & Neuropsychologia Speech Disorders Neurocognitive Disorders Neuropsychological Tests Auditory Perception Parkinson Disease |
| title | Cognitive profile of patients with and without speech impairment in Parkinson's disease |
| title_full | Cognitive profile of patients with and without speech impairment in Parkinson's disease |
| title_fullStr | Cognitive profile of patients with and without speech impairment in Parkinson's disease |
| title_full_unstemmed | Cognitive profile of patients with and without speech impairment in Parkinson's disease |
| title_short | Cognitive profile of patients with and without speech impairment in Parkinson's disease |
| title_sort | cognitive profile of patients with and without speech impairment in parkinson s disease |
| topic | Speech Disorders Neurocognitive Disorders Neuropsychological Tests Auditory Perception Parkinson Disease |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642023000100324&lng=en&tlng=en |
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