The Value of Serum Progesterone Level at The Day of Triggering in Prediction of Intracytoplasmic Sperm Injection [ICSI] Outcome

Background:The potential association of serum progesterone on the day of human chorionic gonadotropin administration with the outcome of intracytoplasmic sperm injection [ICSI] cycles has been one of the major controversies in the endocrinology of ovarian stimulation. Aim of the work: This study wa...

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Main Authors: Mohamed Abo khalil, Mahmoud Farouk Midan, Abdel Aal Mohamed EL-Ghandour, Rashed Moahmed Rashed
Format: Article
Language:English
Published: Al-Azhar University, Faculty of Medicine (Damietta) 2020-10-01
Series:International Journal of Medical Arts
Subjects:
Online Access:https://ijma.journals.ekb.eg/article_108747_1330248d3eba350c57490a85fbf67886.pdf
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author Mohamed Abo khalil
Mahmoud Farouk Midan
Abdel Aal Mohamed EL-Ghandour
Rashed Moahmed Rashed
author_facet Mohamed Abo khalil
Mahmoud Farouk Midan
Abdel Aal Mohamed EL-Ghandour
Rashed Moahmed Rashed
author_sort Mohamed Abo khalil
collection DOAJ
description Background:The potential association of serum progesterone on the day of human chorionic gonadotropin administration with the outcome of intracytoplasmic sperm injection [ICSI] cycles has been one of the major controversies in the endocrinology of ovarian stimulation. Aim of the work: This study was conducted to estimate the net effect of progesterone elevation on the day of human chorionic gonadotrophin [hCG] on pregnancy outcome in women undergoing fresh embryo transfer in control ovarian stimulation using long agonist and antagonist protocols. Patients and Methods:This is a prospective study included a total of 177 patients who were indicated for ICSI. The included cases were divided into three groups according to progesterone level at the day of hCG. Both progesterone and E2 were estimated at the day of triggering. Results:Serum progesterone levels did not differ between cases who got pregnancy and who did not (p=0.435). Estrogen/Progesterone ratio was not significantly different between pregnant and non-pregnant females (p= 0.842).   Conclusion: Progesterone level on the day of hCG administration does not have any effect on ICSI outcome.
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spelling doaj.art-cfef2aab7c5c4f50aa3aa0618df3b8a52022-12-21T20:28:34ZengAl-Azhar University, Faculty of Medicine (Damietta)International Journal of Medical Arts2636-41742682-37802020-10-012479880410.21608/ijma.2020.25117.1107108747The Value of Serum Progesterone Level at The Day of Triggering in Prediction of Intracytoplasmic Sperm Injection [ICSI] OutcomeMohamed Abo khalil0Mahmoud Farouk Midan1Abdel Aal Mohamed EL-Ghandour2Rashed Moahmed Rashed3Department of Obstetrics and Gynecology, El Mahalla General Hospital, Ministry of Health, EgyptDepartment of Obstetrics and Gynecology, Damietta Faculty of Medicine, Al-Azhar University, EgyptInternational Islamic Center for Population Studies and Research, Al-Azhar University, EgyptDepartment of Obstetrics and Gynecology, Damietta Faculty of Medicine, Al-Azhar University, EgyptBackground:The potential association of serum progesterone on the day of human chorionic gonadotropin administration with the outcome of intracytoplasmic sperm injection [ICSI] cycles has been one of the major controversies in the endocrinology of ovarian stimulation. Aim of the work: This study was conducted to estimate the net effect of progesterone elevation on the day of human chorionic gonadotrophin [hCG] on pregnancy outcome in women undergoing fresh embryo transfer in control ovarian stimulation using long agonist and antagonist protocols. Patients and Methods:This is a prospective study included a total of 177 patients who were indicated for ICSI. The included cases were divided into three groups according to progesterone level at the day of hCG. Both progesterone and E2 were estimated at the day of triggering. Results:Serum progesterone levels did not differ between cases who got pregnancy and who did not (p=0.435). Estrogen/Progesterone ratio was not significantly different between pregnant and non-pregnant females (p= 0.842).   Conclusion: Progesterone level on the day of hCG administration does not have any effect on ICSI outcome.https://ijma.journals.ekb.eg/article_108747_1330248d3eba350c57490a85fbf67886.pdfprogesteroneicsiestrogen/progesterone ratiotriggeringoutcome
spellingShingle Mohamed Abo khalil
Mahmoud Farouk Midan
Abdel Aal Mohamed EL-Ghandour
Rashed Moahmed Rashed
The Value of Serum Progesterone Level at The Day of Triggering in Prediction of Intracytoplasmic Sperm Injection [ICSI] Outcome
International Journal of Medical Arts
progesterone
icsi
estrogen/progesterone ratio
triggering
outcome
title The Value of Serum Progesterone Level at The Day of Triggering in Prediction of Intracytoplasmic Sperm Injection [ICSI] Outcome
title_full The Value of Serum Progesterone Level at The Day of Triggering in Prediction of Intracytoplasmic Sperm Injection [ICSI] Outcome
title_fullStr The Value of Serum Progesterone Level at The Day of Triggering in Prediction of Intracytoplasmic Sperm Injection [ICSI] Outcome
title_full_unstemmed The Value of Serum Progesterone Level at The Day of Triggering in Prediction of Intracytoplasmic Sperm Injection [ICSI] Outcome
title_short The Value of Serum Progesterone Level at The Day of Triggering in Prediction of Intracytoplasmic Sperm Injection [ICSI] Outcome
title_sort value of serum progesterone level at the day of triggering in prediction of intracytoplasmic sperm injection icsi outcome
topic progesterone
icsi
estrogen/progesterone ratio
triggering
outcome
url https://ijma.journals.ekb.eg/article_108747_1330248d3eba350c57490a85fbf67886.pdf
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