Germline Variants in DNA Damage Repair Genes: An Emerging Role in the Era of Precision Medicine in Pancreatic Adenocarcinoma

Germline Variants in DNA Damage Repair Genes: An Emerging Role in the Era of Precision Medicine in Pancreatic Adenocarcinoma

Abstract Pancreatic adenocarcinoma is a lethal disease that is projected to become the second most common cause of cancer deaths by 2030. The role of adjuvant therapy after surgical resection has been established by several clinical trials to prolong survival and improve outcomes. Multiagent chemoth...

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Bibliographic Details
Main Authors: Sami Shoucair, Andrew R. Baker, Jun Yu
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Annals of Gastroenterological Surgery
Subjects:
DDR genes
germline variants
pancreatic cancer
precision medicine
Online Access:https://doi.org/10.1002/ags3.12514

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