Selection of antisense oligonucleotides based on multiple predicted target mRNA structures

Selection of antisense oligonucleotides based on multiple predicted target mRNA structures

<p>Abstract</p> <p>Background</p> <p>Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selection methods are limited by uncertainties in RNA secondary structu...

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Bibliographic Details
Main Authors:	Yang Jing, Shu Wenjie, Sun Daochun, Lou Shaoke, Bo Xiaochen, Wang Shengqi
Format:	Article
Language:	English
Published:	BMC 2006-03-01
Series:	BMC Bioinformatics
Online Access:	http://www.biomedcentral.com/1471-2105/7/122

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