Small Non-Coding RNA Profiling Identifies miR-181a-5p as a Mediator of Estrogen Receptor Beta-Induced Inhibition of Cholesterol Biosynthesis in Triple-Negative Breast Cancer

Small Non-Coding RNA Profiling Identifies miR-181a-5p as a Mediator of Estrogen Receptor Beta-Induced Inhibition of Cholesterol Biosynthesis in Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) is a highly heterogeneous disease, representing the most aggressive breast cancer (BC) subtype with limited treatment options due to a lack of estrogen receptor alpha (ERα), progesterone receptor (PR), and Erb-B2 receptor tyrosine kinase 2 (HER2/neu) expression....

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Bibliographic Details
Main Authors: Elena Alexandrova, Jessica Lamberti, Pasquale Saggese, Giovanni Pecoraro, Domenico Memoli, Valeria Mirici Cappa, Maria Ravo, Roberta Iorio, Roberta Tarallo, Francesca Rizzo, Francesca Collina, Monica Cantile, Maurizio Di Bonito, Gerardo Botti, Giovanni Nassa, Alessandro Weisz, Giorgio Giurato
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
triple-negative breast cancer
estrogen receptor beta
small non-coding RNAs
microRNA
cholesterol biosynthesis
Online Access:https://www.mdpi.com/2073-4409/9/4/874

Internet

https://www.mdpi.com/2073-4409/9/4/874

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