CLAVATA3 mediated simultaneous control of transcriptional and post-translational processes provides robustness to the WUSCHEL gradient
WUSCHEL is a critical regulator of stem cell homeostasis at shoot apical meristems. Here the authors show that CLV3 regulates WUSCHEL by not only repressing WUSCHEL transcription but also by controlling nuclear export of WUSCHEL and therefore its diffusion between adjacent cells.
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-11-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-26586-0 |
| _version_ | 1818407588136484864 |
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| author | Alexander Plong Kevin Rodriguez Mark Alber Weitao Chen G. Venugopala Reddy |
| author_facet | Alexander Plong Kevin Rodriguez Mark Alber Weitao Chen G. Venugopala Reddy |
| author_sort | Alexander Plong |
| collection | DOAJ |
| description | WUSCHEL is a critical regulator of stem cell homeostasis at shoot apical meristems. Here the authors show that CLV3 regulates WUSCHEL by not only repressing WUSCHEL transcription but also by controlling nuclear export of WUSCHEL and therefore its diffusion between adjacent cells. |
| first_indexed | 2024-12-14T09:30:13Z |
| format | Article |
| id | doaj.art-cffd650ae02949aab19a9a0a6860b1fb |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-14T09:30:13Z |
| publishDate | 2021-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-cffd650ae02949aab19a9a0a6860b1fb2022-12-21T23:08:05ZengNature PortfolioNature Communications2041-17232021-11-0112111310.1038/s41467-021-26586-0CLAVATA3 mediated simultaneous control of transcriptional and post-translational processes provides robustness to the WUSCHEL gradientAlexander Plong0Kevin Rodriguez1Mark Alber2Weitao Chen3G. Venugopala Reddy4Department of Botany and Plant Sciences, University of California RiversideDepartment of Botany and Plant Sciences, University of California RiversideDepartment of Mathematics, University of California RiversideDepartment of Mathematics, University of California RiversideDepartment of Botany and Plant Sciences, University of California RiversideWUSCHEL is a critical regulator of stem cell homeostasis at shoot apical meristems. Here the authors show that CLV3 regulates WUSCHEL by not only repressing WUSCHEL transcription but also by controlling nuclear export of WUSCHEL and therefore its diffusion between adjacent cells.https://doi.org/10.1038/s41467-021-26586-0 |
| spellingShingle | Alexander Plong Kevin Rodriguez Mark Alber Weitao Chen G. Venugopala Reddy CLAVATA3 mediated simultaneous control of transcriptional and post-translational processes provides robustness to the WUSCHEL gradient Nature Communications |
| title | CLAVATA3 mediated simultaneous control of transcriptional and post-translational processes provides robustness to the WUSCHEL gradient |
| title_full | CLAVATA3 mediated simultaneous control of transcriptional and post-translational processes provides robustness to the WUSCHEL gradient |
| title_fullStr | CLAVATA3 mediated simultaneous control of transcriptional and post-translational processes provides robustness to the WUSCHEL gradient |
| title_full_unstemmed | CLAVATA3 mediated simultaneous control of transcriptional and post-translational processes provides robustness to the WUSCHEL gradient |
| title_short | CLAVATA3 mediated simultaneous control of transcriptional and post-translational processes provides robustness to the WUSCHEL gradient |
| title_sort | clavata3 mediated simultaneous control of transcriptional and post translational processes provides robustness to the wuschel gradient |
| url | https://doi.org/10.1038/s41467-021-26586-0 |
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