Lycopene: A Potent Antioxidant for the Amelioration of Type II Diabetes Mellitus
Nutrition is of utmost importance in chronic disease management and has often been described as the cornerstone of a variety of non-communicable diseases. In particular, type II diabetes mellitus (T2DM) represents a prevalent and global public health crisis. Lycopene, a bright red carotenoid hydroca...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-04-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/27/7/2335 |
| _version_ | 1797438344119975936 |
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| author | Hui Eng Leh Lai Kuan Lee |
| author_facet | Hui Eng Leh Lai Kuan Lee |
| author_sort | Hui Eng Leh |
| collection | DOAJ |
| description | Nutrition is of utmost importance in chronic disease management and has often been described as the cornerstone of a variety of non-communicable diseases. In particular, type II diabetes mellitus (T2DM) represents a prevalent and global public health crisis. Lycopene, a bright red carotenoid hydrocarbon found in tomatoes and other red fruits and vegetables, has been extensively studied for its biological activities and treatment efficiency in diabetes care. Epidemiological investigations indicate that lycopene has potential antioxidant properties, is capable of scavenging reactive species, and alleviates oxidative stress in T2DM patients. This review aims to summarize the characteristics and mechanisms of action of lycopene as a potent antioxidant for T2DM. In addition, the evidence demonstrating the effects of lycopene on glycemic control and oxidative stress biomarkers in T2DM are also highlighted using animal and human studies as literature approach. |
| first_indexed | 2024-03-09T11:36:18Z |
| format | Article |
| id | doaj.art-cffdd6251ba548a79930fab2b8ff8421 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-09T11:36:18Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-cffdd6251ba548a79930fab2b8ff84212023-11-30T23:42:51ZengMDPI AGMolecules1420-30492022-04-01277233510.3390/molecules27072335Lycopene: A Potent Antioxidant for the Amelioration of Type II Diabetes MellitusHui Eng Leh0Lai Kuan Lee1Food Technology Program, School of Industrial Technology, Universiti Sains Malaysia, Gelugor 11800, Pulau Pinang, MalaysiaFood Technology Program, School of Industrial Technology, Universiti Sains Malaysia, Gelugor 11800, Pulau Pinang, MalaysiaNutrition is of utmost importance in chronic disease management and has often been described as the cornerstone of a variety of non-communicable diseases. In particular, type II diabetes mellitus (T2DM) represents a prevalent and global public health crisis. Lycopene, a bright red carotenoid hydrocarbon found in tomatoes and other red fruits and vegetables, has been extensively studied for its biological activities and treatment efficiency in diabetes care. Epidemiological investigations indicate that lycopene has potential antioxidant properties, is capable of scavenging reactive species, and alleviates oxidative stress in T2DM patients. This review aims to summarize the characteristics and mechanisms of action of lycopene as a potent antioxidant for T2DM. In addition, the evidence demonstrating the effects of lycopene on glycemic control and oxidative stress biomarkers in T2DM are also highlighted using animal and human studies as literature approach.https://www.mdpi.com/1420-3049/27/7/2335antioxidantcomplementary medicinelycopeneoxidative stresstype II diabetes mellitus |
| spellingShingle | Hui Eng Leh Lai Kuan Lee Lycopene: A Potent Antioxidant for the Amelioration of Type II Diabetes Mellitus Molecules antioxidant complementary medicine lycopene oxidative stress type II diabetes mellitus |
| title | Lycopene: A Potent Antioxidant for the Amelioration of Type II Diabetes Mellitus |
| title_full | Lycopene: A Potent Antioxidant for the Amelioration of Type II Diabetes Mellitus |
| title_fullStr | Lycopene: A Potent Antioxidant for the Amelioration of Type II Diabetes Mellitus |
| title_full_unstemmed | Lycopene: A Potent Antioxidant for the Amelioration of Type II Diabetes Mellitus |
| title_short | Lycopene: A Potent Antioxidant for the Amelioration of Type II Diabetes Mellitus |
| title_sort | lycopene a potent antioxidant for the amelioration of type ii diabetes mellitus |
| topic | antioxidant complementary medicine lycopene oxidative stress type II diabetes mellitus |
| url | https://www.mdpi.com/1420-3049/27/7/2335 |
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