Prevalence of Herpes Simplex Virus Type 1 and 2 (HSV-1 and HSV-2) in the Women with Breast Cancer by Multiplex-PCR method
Introduction: Breast cancer is a common malignancy and a major cause of death in women. Viruses are considered as one of the risk factors associated with breast cancer. Herpes simplex virus-1 (HSV-1) and HSV-2 are involved in the pathogenesis of cancer. The present study was conducted to determine t...
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| Format: | Article |
| Language: | fas |
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Mashhad University of Medical Sciences
2018-05-01
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| Series: | Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān |
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| Online Access: | https://ijogi.mums.ac.ir/article_11070_8ea7e46d930bf2ca48ffdc53d0ab3144.pdf |
| _version_ | 1811328555083104256 |
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| author | Fatemeh Kaveh Kumarss Amini Mojtaba Sadeh |
| author_facet | Fatemeh Kaveh Kumarss Amini Mojtaba Sadeh |
| author_sort | Fatemeh Kaveh |
| collection | DOAJ |
| description | Introduction: Breast cancer is a common malignancy and a major cause of death in women. Viruses are considered as one of the risk factors associated with breast cancer. Herpes simplex virus-1 (HSV-1) and HSV-2 are involved in the pathogenesis of cancer. The present study was conducted to determine the frequency of HSV-1 and HSV-2 in the blood samples of patients with breast cancer using multiplex-polymerase chain reaction (M-PCR) technique.
methods: This cross-sectional study was conducted on 60 breast cancer patients within 2014-2015. The infection with HSV-1 and HSV-2 was investigated by M-PCR. All data were analyzed using SPSS software (version 18).
Results: Out of the 60 blood samples obtained from patients with breast cancer, 6 (10%) and 3 (5%) samples were positive for HSV-1 and HSV-2, respectively.
Conclusion: herpes simplex virus, especially HSV-1, can play a role as a cofactor in the incidence of breast cancer, so further studies are recommended in this area. |
| first_indexed | 2024-04-13T15:27:10Z |
| format | Article |
| id | doaj.art-cffe6bc7d48c4636b770f0345a87257d |
| institution | Directory Open Access Journal |
| issn | 1680-2993 2008-2363 |
| language | fas |
| last_indexed | 2024-04-13T15:27:10Z |
| publishDate | 2018-05-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān |
| spelling | doaj.art-cffe6bc7d48c4636b770f0345a87257d2022-12-22T02:41:28ZfasMashhad University of Medical SciencesMajallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān1680-29932008-23632018-05-01213394410.22038/ijogi.2018.1107011070Prevalence of Herpes Simplex Virus Type 1 and 2 (HSV-1 and HSV-2) in the Women with Breast Cancer by Multiplex-PCR methodFatemeh Kaveh0Kumarss Amini1Mojtaba Sadeh2M.Sc. in Microbiology, School of Basic Sciences, Saveh Branch, Islamic Azad University, Saveh, Iran.Assistant Professor, Department of Microbiology, School of Basic Sciences, Saveh Branch, Islamic Azad University, Saveh, Iran.Medical Bacteriology Specialist, Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Introduction: Breast cancer is a common malignancy and a major cause of death in women. Viruses are considered as one of the risk factors associated with breast cancer. Herpes simplex virus-1 (HSV-1) and HSV-2 are involved in the pathogenesis of cancer. The present study was conducted to determine the frequency of HSV-1 and HSV-2 in the blood samples of patients with breast cancer using multiplex-polymerase chain reaction (M-PCR) technique. methods: This cross-sectional study was conducted on 60 breast cancer patients within 2014-2015. The infection with HSV-1 and HSV-2 was investigated by M-PCR. All data were analyzed using SPSS software (version 18). Results: Out of the 60 blood samples obtained from patients with breast cancer, 6 (10%) and 3 (5%) samples were positive for HSV-1 and HSV-2, respectively. Conclusion: herpes simplex virus, especially HSV-1, can play a role as a cofactor in the incidence of breast cancer, so further studies are recommended in this area.https://ijogi.mums.ac.ir/article_11070_8ea7e46d930bf2ca48ffdc53d0ab3144.pdfbreast cancerherpes simplex virusmultiplex-pcr |
| spellingShingle | Fatemeh Kaveh Kumarss Amini Mojtaba Sadeh Prevalence of Herpes Simplex Virus Type 1 and 2 (HSV-1 and HSV-2) in the Women with Breast Cancer by Multiplex-PCR method Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān breast cancer herpes simplex virus multiplex-pcr |
| title | Prevalence of Herpes Simplex Virus Type 1 and 2 (HSV-1 and HSV-2) in the Women with Breast Cancer by Multiplex-PCR method |
| title_full | Prevalence of Herpes Simplex Virus Type 1 and 2 (HSV-1 and HSV-2) in the Women with Breast Cancer by Multiplex-PCR method |
| title_fullStr | Prevalence of Herpes Simplex Virus Type 1 and 2 (HSV-1 and HSV-2) in the Women with Breast Cancer by Multiplex-PCR method |
| title_full_unstemmed | Prevalence of Herpes Simplex Virus Type 1 and 2 (HSV-1 and HSV-2) in the Women with Breast Cancer by Multiplex-PCR method |
| title_short | Prevalence of Herpes Simplex Virus Type 1 and 2 (HSV-1 and HSV-2) in the Women with Breast Cancer by Multiplex-PCR method |
| title_sort | prevalence of herpes simplex virus type 1 and 2 hsv 1 and hsv 2 in the women with breast cancer by multiplex pcr method |
| topic | breast cancer herpes simplex virus multiplex-pcr |
| url | https://ijogi.mums.ac.ir/article_11070_8ea7e46d930bf2ca48ffdc53d0ab3144.pdf |
| work_keys_str_mv | AT fatemehkaveh prevalenceofherpessimplexvirustype1and2hsv1andhsv2inthewomenwithbreastcancerbymultiplexpcrmethod AT kumarssamini prevalenceofherpessimplexvirustype1and2hsv1andhsv2inthewomenwithbreastcancerbymultiplexpcrmethod AT mojtabasadeh prevalenceofherpessimplexvirustype1and2hsv1andhsv2inthewomenwithbreastcancerbymultiplexpcrmethod |