CLINICAL ADVANTAGES OF TELMISARTAN: FEATURES OF PHARMACOKINETICS, PHARMACODYNAMICS AND EFFECTS ON THE DAILY BLOOD PRESSURE PROFILE
The features of the pharmacokinetics of the angiotensin II receptor blocker telmisartan are considered. Thanks to these features it has a number of advantages in comparison with other angiotensin II receptor blockers and antihypertensive drugs from other classes. Particular attention is paid to the...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Столичная издательская компания
2017-09-01
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| Series: | Рациональная фармакотерапия в кардиологии |
| Subjects: | |
| Online Access: | https://www.rpcardio.online/jour/article/view/1517 |
| _version_ | 1797232186253901824 |
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| author | O. D. Ostroumova E. A. Smolyarchuk O. V. Bondarec E. E. Paleeva |
| author_facet | O. D. Ostroumova E. A. Smolyarchuk O. V. Bondarec E. E. Paleeva |
| author_sort | O. D. Ostroumova |
| collection | DOAJ |
| description | The features of the pharmacokinetics of the angiotensin II receptor blocker telmisartan are considered. Thanks to these features it has a number of advantages in comparison with other angiotensin II receptor blockers and antihypertensive drugs from other classes. Particular attention is paid to the long half-life of telmisartan, which retains its effect for more than 24 hours. This is especially important for controlling blood pressure (BP) in the early morning hours. Data from studies demonstrating that excessive BP rises in the early morning hours increase the risk of cardiovascular and cerebrovascular complications are presented. The results of comparative studies of telmisartan using the ambulatory BP monitoring, which testify to its advantages in BP control within 24-hours, are considered. |
| first_indexed | 2024-03-08T14:02:30Z |
| format | Article |
| id | doaj.art-d00895edf2be43b7bebe8bab44c0f4af |
| institution | Directory Open Access Journal |
| issn | 1819-6446 2225-3653 |
| language | English |
| last_indexed | 2024-04-24T15:56:16Z |
| publishDate | 2017-09-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj.art-d00895edf2be43b7bebe8bab44c0f4af2024-04-01T07:43:35ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532017-09-0113455055710.20996/1819-6446-2017-13-4-550-5571375CLINICAL ADVANTAGES OF TELMISARTAN: FEATURES OF PHARMACOKINETICS, PHARMACODYNAMICS AND EFFECTS ON THE DAILY BLOOD PRESSURE PROFILEO. D. Ostroumova0E. A. Smolyarchuk1O. V. Bondarec2E. E. Paleeva3A.I. Evdokimov Moscow State University of Medicine and Dentistry; I.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityA.I. Evdokimov Moscow State University of Medicine and DentistryA.I. Evdokimov Moscow State University of Medicine and DentistryThe features of the pharmacokinetics of the angiotensin II receptor blocker telmisartan are considered. Thanks to these features it has a number of advantages in comparison with other angiotensin II receptor blockers and antihypertensive drugs from other classes. Particular attention is paid to the long half-life of telmisartan, which retains its effect for more than 24 hours. This is especially important for controlling blood pressure (BP) in the early morning hours. Data from studies demonstrating that excessive BP rises in the early morning hours increase the risk of cardiovascular and cerebrovascular complications are presented. The results of comparative studies of telmisartan using the ambulatory BP monitoring, which testify to its advantages in BP control within 24-hours, are considered.https://www.rpcardio.online/jour/article/view/1517arterial hypertensionambulatory blood pressure monitoringmorning blood pressure surgeadherence to treatmenttelmisartan |
| spellingShingle | O. D. Ostroumova E. A. Smolyarchuk O. V. Bondarec E. E. Paleeva CLINICAL ADVANTAGES OF TELMISARTAN: FEATURES OF PHARMACOKINETICS, PHARMACODYNAMICS AND EFFECTS ON THE DAILY BLOOD PRESSURE PROFILE Рациональная фармакотерапия в кардиологии arterial hypertension ambulatory blood pressure monitoring morning blood pressure surge adherence to treatment telmisartan |
| title | CLINICAL ADVANTAGES OF TELMISARTAN: FEATURES OF PHARMACOKINETICS, PHARMACODYNAMICS AND EFFECTS ON THE DAILY BLOOD PRESSURE PROFILE |
| title_full | CLINICAL ADVANTAGES OF TELMISARTAN: FEATURES OF PHARMACOKINETICS, PHARMACODYNAMICS AND EFFECTS ON THE DAILY BLOOD PRESSURE PROFILE |
| title_fullStr | CLINICAL ADVANTAGES OF TELMISARTAN: FEATURES OF PHARMACOKINETICS, PHARMACODYNAMICS AND EFFECTS ON THE DAILY BLOOD PRESSURE PROFILE |
| title_full_unstemmed | CLINICAL ADVANTAGES OF TELMISARTAN: FEATURES OF PHARMACOKINETICS, PHARMACODYNAMICS AND EFFECTS ON THE DAILY BLOOD PRESSURE PROFILE |
| title_short | CLINICAL ADVANTAGES OF TELMISARTAN: FEATURES OF PHARMACOKINETICS, PHARMACODYNAMICS AND EFFECTS ON THE DAILY BLOOD PRESSURE PROFILE |
| title_sort | clinical advantages of telmisartan features of pharmacokinetics pharmacodynamics and effects on the daily blood pressure profile |
| topic | arterial hypertension ambulatory blood pressure monitoring morning blood pressure surge adherence to treatment telmisartan |
| url | https://www.rpcardio.online/jour/article/view/1517 |
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