Correlating Serum Beta hCG Levels with Transvaginal Sonographic Features of Ectopic Pregnancy

To correlate Beta Hcg Levels with transvaginal sonographic features of ectopic pregnancy Methods: In this prospective study 204 patients with confirmed diagnosis of ectopic pregnancy (EP), by both trasnvaginal sonography (TVS) and histopathology were included . Results of TVS and serum βHCG levels w...

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Main Author: Uzma Saeed
Format: Article
Language:English
Published: Rawalpindi Medical University 2017-03-01
Series:Journal of Rawalpindi Medical College
Subjects:
Online Access:https://www.journalrmc.com/index.php/JRMC/article/view/111
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author Uzma Saeed
author_facet Uzma Saeed
author_sort Uzma Saeed
collection DOAJ
description To correlate Beta Hcg Levels with transvaginal sonographic features of ectopic pregnancy Methods: In this prospective study 204 patients with confirmed diagnosis of ectopic pregnancy (EP), by both trasnvaginal sonography (TVS) and histopathology were included . Results of TVS and serum βHCG levels were obtained. Other variables were age, gestational age, size, site and volume of EP, fetal cardiac activity and presence or absence of pelvic ascites. Results: Sensitivity and specificity of TVS for detection of EP was 98% and 87.5% respectively. The values of median and range for the age, gestational age, βHCG and volume of EP were 29 (17-43) years, 5(4-6) weeks, 3248.5 (14-53048) IU/L, 8648.36 (268- 80491) mm3 respectively. Most common site of EP was adnexa (93.6%) and most common side was right (52%). Fetal cardiac activity was evident in 4.4% cases and pelvic ascites was present in 64.7% cases. There was no significant difference between two βHCG groups (<2000, >2000) in terms of qualitative and quantitative variables except the volume of EP which was significantly different among groups (p value <0.0001). Conclusion: Serum βHCG level alone cannot diagnose or exclude EP confidently and it is significantly correlated with the size of EP. The combination of serum βHCG and TVS provide highly accurate diagnostic information.
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spelling doaj.art-d00cac2b6ec84326a884e776864a28132022-12-21T21:05:18ZengRawalpindi Medical UniversityJournal of Rawalpindi Medical College1683-35621683-35702017-03-01211Correlating Serum Beta hCG Levels with Transvaginal Sonographic Features of Ectopic PregnancyUzma Saeed0Department of Radiology,Dallah Hospital,Riyadh, Saudi ArabiaTo correlate Beta Hcg Levels with transvaginal sonographic features of ectopic pregnancy Methods: In this prospective study 204 patients with confirmed diagnosis of ectopic pregnancy (EP), by both trasnvaginal sonography (TVS) and histopathology were included . Results of TVS and serum βHCG levels were obtained. Other variables were age, gestational age, size, site and volume of EP, fetal cardiac activity and presence or absence of pelvic ascites. Results: Sensitivity and specificity of TVS for detection of EP was 98% and 87.5% respectively. The values of median and range for the age, gestational age, βHCG and volume of EP were 29 (17-43) years, 5(4-6) weeks, 3248.5 (14-53048) IU/L, 8648.36 (268- 80491) mm3 respectively. Most common site of EP was adnexa (93.6%) and most common side was right (52%). Fetal cardiac activity was evident in 4.4% cases and pelvic ascites was present in 64.7% cases. There was no significant difference between two βHCG groups (<2000, >2000) in terms of qualitative and quantitative variables except the volume of EP which was significantly different among groups (p value <0.0001). Conclusion: Serum βHCG level alone cannot diagnose or exclude EP confidently and it is significantly correlated with the size of EP. The combination of serum βHCG and TVS provide highly accurate diagnostic information.https://www.journalrmc.com/index.php/JRMC/article/view/111PregnancyEctopicChorionic GonadotropinTransvaginal ultrasonography
spellingShingle Uzma Saeed
Correlating Serum Beta hCG Levels with Transvaginal Sonographic Features of Ectopic Pregnancy
Journal of Rawalpindi Medical College
Pregnancy
Ectopic
Chorionic Gonadotropin
Transvaginal ultrasonography
title Correlating Serum Beta hCG Levels with Transvaginal Sonographic Features of Ectopic Pregnancy
title_full Correlating Serum Beta hCG Levels with Transvaginal Sonographic Features of Ectopic Pregnancy
title_fullStr Correlating Serum Beta hCG Levels with Transvaginal Sonographic Features of Ectopic Pregnancy
title_full_unstemmed Correlating Serum Beta hCG Levels with Transvaginal Sonographic Features of Ectopic Pregnancy
title_short Correlating Serum Beta hCG Levels with Transvaginal Sonographic Features of Ectopic Pregnancy
title_sort correlating serum beta hcg levels with transvaginal sonographic features of ectopic pregnancy
topic Pregnancy
Ectopic
Chorionic Gonadotropin
Transvaginal ultrasonography
url https://www.journalrmc.com/index.php/JRMC/article/view/111
work_keys_str_mv AT uzmasaeed correlatingserumbetahcglevelswithtransvaginalsonographicfeaturesofectopicpregnancy