Nosocomial infections in a neonatal intensive care unit during 16 years: 1997-2012
Introduction Surveillance of nosocomial infections (NIs) is an essential part of quality patient care; however, there are few reports of National Healthcare Safety Network (NHSN) surveillance in neonatal intensive care units (NICUs) and none in developing countries. The purpose of this study was to...
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Sociedade Brasileira de Medicina Tropical (SBMT)
2014-06-01
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| Series: | Revista da Sociedade Brasileira de Medicina Tropical |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000300321&lng=en&tlng=en |
| _version_ | 1811232753459396608 |
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| author | Jane Eire Urzedo Maria Margarida Morena Domingos Levenhagen Reginaldo Santos Pedroso Vânia Olivetti Steffen Abdallah Sebastiana Silva Sabino Denise Von Dolinger Brito |
| author_facet | Jane Eire Urzedo Maria Margarida Morena Domingos Levenhagen Reginaldo Santos Pedroso Vânia Olivetti Steffen Abdallah Sebastiana Silva Sabino Denise Von Dolinger Brito |
| author_sort | Jane Eire Urzedo |
| collection | DOAJ |
| description | Introduction Surveillance of nosocomial infections (NIs) is an essential part of quality patient care; however, there are few reports of National Healthcare Safety Network (NHSN) surveillance in neonatal intensive care units (NICUs) and none in developing countries. The purpose of this study was to report the incidence of NIs, causative organisms, and antimicrobial susceptibility patterns in a large cohort of neonates admitted to the NICU during a 16-year period. Methods The patients were followed 5 times per week from birth to discharge or death, and epidemiological surveillance was conducted according to the NHSN. Results From January 1997 to December 2012, 4,615 neonates, representing 62,412 patient-days, were admitted to the NICU. The device-associated infection rates were as follows: 17.3 primary bloodstream infections per 1,000 central line-days and 3.2 pneumonia infections per 1,000 ventilator-days. A total of 1,182 microorganisms were isolated from sterile body site cultures in 902 neonates. Coagulase-negative staphylococci (CoNS) (34.3%) and Staphylococcus aureus (15.6%) were the most common etiologic agents isolated from cultures. The incidences of oxacillin-resistant CoNS and Staphylococcus aureus were 86.4% and 28.3%, respectively. Conclusions The most important NI remains bloodstream infection with staphylococci as the predominant pathogens, observed at much higher rates than those reported in the literature. Multiresistant microorganisms, especially oxacillin-resistant staphylococci and gram-negative bacilli resistant to cephalosporin were frequently found. Furthermore, by promoting strict hygiene measures and meticulous care of the infected infants, the process itself of evaluating the causative organisms was valuable. |
| first_indexed | 2024-04-12T11:08:24Z |
| format | Article |
| id | doaj.art-d01267bcd23645c588ca197a217f1e2e |
| institution | Directory Open Access Journal |
| issn | 1678-9849 |
| language | English |
| last_indexed | 2024-04-12T11:08:24Z |
| publishDate | 2014-06-01 |
| publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
| record_format | Article |
| series | Revista da Sociedade Brasileira de Medicina Tropical |
| spelling | doaj.art-d01267bcd23645c588ca197a217f1e2e2022-12-22T03:35:40ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98492014-06-0147332132610.1590/0037-8682-0101-2014S0037-86822014000300321Nosocomial infections in a neonatal intensive care unit during 16 years: 1997-2012Jane Eire UrzedoMaria Margarida Morena Domingos LevenhagenReginaldo Santos PedrosoVânia Olivetti Steffen AbdallahSebastiana Silva SabinoDenise Von Dolinger BritoIntroduction Surveillance of nosocomial infections (NIs) is an essential part of quality patient care; however, there are few reports of National Healthcare Safety Network (NHSN) surveillance in neonatal intensive care units (NICUs) and none in developing countries. The purpose of this study was to report the incidence of NIs, causative organisms, and antimicrobial susceptibility patterns in a large cohort of neonates admitted to the NICU during a 16-year period. Methods The patients were followed 5 times per week from birth to discharge or death, and epidemiological surveillance was conducted according to the NHSN. Results From January 1997 to December 2012, 4,615 neonates, representing 62,412 patient-days, were admitted to the NICU. The device-associated infection rates were as follows: 17.3 primary bloodstream infections per 1,000 central line-days and 3.2 pneumonia infections per 1,000 ventilator-days. A total of 1,182 microorganisms were isolated from sterile body site cultures in 902 neonates. Coagulase-negative staphylococci (CoNS) (34.3%) and Staphylococcus aureus (15.6%) were the most common etiologic agents isolated from cultures. The incidences of oxacillin-resistant CoNS and Staphylococcus aureus were 86.4% and 28.3%, respectively. Conclusions The most important NI remains bloodstream infection with staphylococci as the predominant pathogens, observed at much higher rates than those reported in the literature. Multiresistant microorganisms, especially oxacillin-resistant staphylococci and gram-negative bacilli resistant to cephalosporin were frequently found. Furthermore, by promoting strict hygiene measures and meticulous care of the infected infants, the process itself of evaluating the causative organisms was valuable.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000300321&lng=en&tlng=enNosocomial infectionSurveillance systemCritical neonates |
| spellingShingle | Jane Eire Urzedo Maria Margarida Morena Domingos Levenhagen Reginaldo Santos Pedroso Vânia Olivetti Steffen Abdallah Sebastiana Silva Sabino Denise Von Dolinger Brito Nosocomial infections in a neonatal intensive care unit during 16 years: 1997-2012 Revista da Sociedade Brasileira de Medicina Tropical Nosocomial infection Surveillance system Critical neonates |
| title | Nosocomial infections in a neonatal intensive care unit during 16 years: 1997-2012 |
| title_full | Nosocomial infections in a neonatal intensive care unit during 16 years: 1997-2012 |
| title_fullStr | Nosocomial infections in a neonatal intensive care unit during 16 years: 1997-2012 |
| title_full_unstemmed | Nosocomial infections in a neonatal intensive care unit during 16 years: 1997-2012 |
| title_short | Nosocomial infections in a neonatal intensive care unit during 16 years: 1997-2012 |
| title_sort | nosocomial infections in a neonatal intensive care unit during 16 years 1997 2012 |
| topic | Nosocomial infection Surveillance system Critical neonates |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000300321&lng=en&tlng=en |
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