Application of Nicotinamide to Culture Medium Improves the Efficiency of Genome Editing in Hexaploid Wheat

Application of Nicotinamide to Culture Medium Improves the Efficiency of Genome Editing in Hexaploid Wheat

Histone acetylation is the earliest and most well-characterized of post-translation modifications. It is mediated by histone acetyltransferases (HAT) and histone deacetylases (HDAC). Histone acetylation could change the chromatin structure and status and further regulate gene transcription. In this...

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Bibliographic Details
Main Authors: Wanxin Wang, Peipei Huang, Wenshuang Dai, Huali Tang, Yuliang Qiu, Yanan Chang, Zhiyang Han, Xi Li, Lipu Du, Xingguo Ye, Cheng Zou, Ke Wang
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
nicotinamide
wheat
CRISPR/Cas9
histone deacetylase inhibitors
editing efficiency
base editing
Online Access:https://www.mdpi.com/1422-0067/24/5/4416

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https://www.mdpi.com/1422-0067/24/5/4416

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