IL-2/CD25 axis mediates cellular networks promoting the growth of CD25+ acute myeloid leukemia cells
Although the expression of interleukin-2 receptor α-chain (IL-2Rα, CD25) has been provided prognostic significance independent of known biomarkers in acute myeloid leukemia (AML), the functional role of CD25 molecule remains unknown. Since IL-2 can be trans-presented via CD25 to another cell, CD25+A...
Main Authors: | Kazunori Nakase, Kenkichi Kita |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2024-01-01
|
Series: | Leukemia Research Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S221304892400044X |
Similar Items
-
CD25 targeting with the afucosylated human IgG1 antibody RG6292 eliminates regulatory T cells and CD25+ blasts in acute myeloid leukemia
by: Laurène Pousse, et al.
Published: (2023-05-01) -
Harnessing Macrophages through the Blockage of CD47: Implications for Acute Myeloid Leukemia
by: Luciana Melo Garcia, et al.
Published: (2021-12-01) -
Expression of CD71 by flow cytometry in acute leukemias: More often seen in acute myeloid leukemia
by: Amit Pande, et al.
Published: (2016-01-01) -
Uncommon CD markers in acute myeloid leukemia
by: Azad Abul Kalam, et al.
Published: (2018-12-01) -
Evaluation of CD96 and CD123 in CD34+ leukemic stem cells in acute myeloid leukemia patients and their relation to response to induction therapy
by: Haidar H Al-Fatlawi, et al.
Published: (2016-01-01)