Тhe study of Association of gene polymorphism with sports success and risk of alimentary-dependent diseases in athletes representing cyclic sports
The studies of genetic polymorphisms rs1815739 (ACTN3 gene), rs2016520 (gene PPARD), rs1042713 (ADRB2 gene), rs1799945 (HFE gene), rs1801282 (PPARG gene) of athletes involved in cyclic sports were carried out. Genotyping was performed using allele-specific amplification with real-time detection of r...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
National Electronic Information Consortium (NEICON)
2020-08-01
|
Series: | Спортивная медицина: наука и практика |
Subjects: | |
Online Access: | https://www.smjournal.ru/jour/article/view/169 |
_version_ | 1797372541271015424 |
---|---|
author | E. Yu. Sorokina E. E. Keshabyants N. N. Denisova |
author_facet | E. Yu. Sorokina E. E. Keshabyants N. N. Denisova |
author_sort | E. Yu. Sorokina |
collection | DOAJ |
description | The studies of genetic polymorphisms rs1815739 (ACTN3 gene), rs2016520 (gene PPARD), rs1042713 (ADRB2 gene), rs1799945 (HFE gene), rs1801282 (PPARG gene) of athletes involved in cyclic sports were carried out. Genotyping was performed using allele-specific amplification with real-time detection of results and the use of TaqMan probes. As a result of the research, a higher incidence of alleles associated with endurance (T-polymorphism rs1815739 and G - polymorphism rs2016520) was revealed in athletes of cyclic sports. The analysis of the results of genetic polymorphisms: rs9939609 gene FTO, ADRB3 rs4994 gene rs2228570 and VDR gene showed that the risk of development of alimentary-related diseases (obesity and osteoporosis) in the examined athletes after sports career is lower than in the General population. |
first_indexed | 2024-03-08T18:37:24Z |
format | Article |
id | doaj.art-d013ae7494a643e0adb8ed3d9f9e3463 |
institution | Directory Open Access Journal |
issn | 2223-2524 2587-9014 |
language | English |
last_indexed | 2024-03-08T18:37:24Z |
publishDate | 2020-08-01 |
publisher | National Electronic Information Consortium (NEICON) |
record_format | Article |
series | Спортивная медицина: наука и практика |
spelling | doaj.art-d013ae7494a643e0adb8ed3d9f9e34632023-12-29T11:27:47ZengNational Electronic Information Consortium (NEICON)Спортивная медицина: наука и практика2223-25242587-90142020-08-0193414810.17238/ISSN2223-2524.2019.3.41168Тhe study of Association of gene polymorphism with sports success and risk of alimentary-dependent diseases in athletes representing cyclic sportsE. Yu. Sorokina0E. E. Keshabyants1N. N. Denisova2Federal Research Centre of Nutrition, Biotechnology and Food SafetyFederal Research Centre of Nutrition, Biotechnology and Food SafetyFederal Research Centre of Nutrition, Biotechnology and Food SafetyThe studies of genetic polymorphisms rs1815739 (ACTN3 gene), rs2016520 (gene PPARD), rs1042713 (ADRB2 gene), rs1799945 (HFE gene), rs1801282 (PPARG gene) of athletes involved in cyclic sports were carried out. Genotyping was performed using allele-specific amplification with real-time detection of results and the use of TaqMan probes. As a result of the research, a higher incidence of alleles associated with endurance (T-polymorphism rs1815739 and G - polymorphism rs2016520) was revealed in athletes of cyclic sports. The analysis of the results of genetic polymorphisms: rs9939609 gene FTO, ADRB3 rs4994 gene rs2228570 and VDR gene showed that the risk of development of alimentary-related diseases (obesity and osteoporosis) in the examined athletes after sports career is lower than in the General population.https://www.smjournal.ru/jour/article/view/169cyclic sportsgene polymorphismsports success |
spellingShingle | E. Yu. Sorokina E. E. Keshabyants N. N. Denisova Тhe study of Association of gene polymorphism with sports success and risk of alimentary-dependent diseases in athletes representing cyclic sports Спортивная медицина: наука и практика cyclic sports gene polymorphism sports success |
title | Тhe study of Association of gene polymorphism with sports success and risk of alimentary-dependent diseases in athletes representing cyclic sports |
title_full | Тhe study of Association of gene polymorphism with sports success and risk of alimentary-dependent diseases in athletes representing cyclic sports |
title_fullStr | Тhe study of Association of gene polymorphism with sports success and risk of alimentary-dependent diseases in athletes representing cyclic sports |
title_full_unstemmed | Тhe study of Association of gene polymorphism with sports success and risk of alimentary-dependent diseases in athletes representing cyclic sports |
title_short | Тhe study of Association of gene polymorphism with sports success and risk of alimentary-dependent diseases in athletes representing cyclic sports |
title_sort | тhe study of association of gene polymorphism with sports success and risk of alimentary dependent diseases in athletes representing cyclic sports |
topic | cyclic sports gene polymorphism sports success |
url | https://www.smjournal.ru/jour/article/view/169 |
work_keys_str_mv | AT eyusorokina thestudyofassociationofgenepolymorphismwithsportssuccessandriskofalimentarydependentdiseasesinathletesrepresentingcyclicsports AT eekeshabyants thestudyofassociationofgenepolymorphismwithsportssuccessandriskofalimentarydependentdiseasesinathletesrepresentingcyclicsports AT nndenisova thestudyofassociationofgenepolymorphismwithsportssuccessandriskofalimentarydependentdiseasesinathletesrepresentingcyclicsports |