Ginsenoside Rg1 Ameliorates Neuroinflammation via Suppression of Connexin43 Ubiquitination to Attenuate Depression

Ginsenoside Rg1 Ameliorates Neuroinflammation via Suppression of Connexin43 Ubiquitination to Attenuate Depression

Depression is an inflammation-associated disease that results in major depression as inflammation increases and progresses. Ginsenoside Rg1 (Rg1), the major bioactive ingredient derived from ginseng, possesses remarkable anti-depressant and anti-inflammatory effects. Our previous studies showed that...

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Bibliographic Details
Main Authors: Huiqin Wang, Yantao Yang, Songwei Yang, Siyu Ren, Juling Feng, Yangbo Liu, Haodong Chen, Naihong Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Pharmacology
Subjects:
depression
inflammation
ginsenoside Rg1
connexin 43
ubiquitination
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.709019/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.709019/full

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