Human Bronchial Epithelial Cells Induce CD141/CD123/DC-SIGN/FLT3 Monocytes That Promote Allogeneic Th17 Differentiation

Human Bronchial Epithelial Cells Induce CD141/CD123/DC-SIGN/FLT3 Monocytes That Promote Allogeneic Th17 Differentiation

Little is known about monocyte differentiation in the lung mucosal environment and about how the epithelium shapes monocyte function. We studied the role of the soluble component of bronchial epithelial cells (BECs) obtained under basal culture conditions in innate and adaptive monocyte responses. M...

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Bibliographic Details
Main Authors:	Carolina Obregon, Amiq Gazdhar, Fabian Blank, Valerie Cesson, Alban Lovis, John David Aubert, Romain Lazor, Francois Spertini, Anne Wilson, Katrin Hostettler, Laurent P. Nicod
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-04-01
Series:	Frontiers in Immunology
Subjects:	bronchial epithelial cell-conditioned media monocytes monocyte-derived dendritic cell Th17 interleukin-17 IL-1β
Online Access:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.00447/full

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