Recurrent primary orbital well-differentiated liposarcoma /atypical lipomatous tumor: A rare case report with six-year follow-up

Purpose: We report a case with over 6 years of follow-up for well-differentiated liposarcoma or atypical lipomatous tumor (WDL/ALT). Observations: Over a 6-year time course, a patient with a recurrent right orbital mass was biopsied/debulked four times. It was not until the fourth biopsy that a diag...

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Main Authors: Frank Mei, Lin He, Parsha Forouzan, Ronald Mancini, Robert Nick Hogan
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:American Journal of Ophthalmology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2451993622003486
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author Frank Mei
Lin He
Parsha Forouzan
Ronald Mancini
Robert Nick Hogan
author_facet Frank Mei
Lin He
Parsha Forouzan
Ronald Mancini
Robert Nick Hogan
author_sort Frank Mei
collection DOAJ
description Purpose: We report a case with over 6 years of follow-up for well-differentiated liposarcoma or atypical lipomatous tumor (WDL/ALT). Observations: Over a 6-year time course, a patient with a recurrent right orbital mass was biopsied/debulked four times. It was not until the fourth biopsy that a diagnosis of WDL/ALT was obtained. Throughout the time course, the patient maintained good vision and there has been no evidence of dedifferentiation or metastasis thus far. Conclusions: The diagnosis of WDL/ALT sound be considered in the cases of a recurrent orbit mass when pathology continually shows nonspecific fibrofatty tissue with chronic inflammatory changes.
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spelling doaj.art-d01c6866082a494eba4a9c567f52849a2022-12-22T01:28:24ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362022-09-0127101602Recurrent primary orbital well-differentiated liposarcoma /atypical lipomatous tumor: A rare case report with six-year follow-upFrank Mei0Lin He1Parsha Forouzan2Ronald Mancini3Robert Nick Hogan4Department of Ophthalmology. University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, TX, 75390, Dallas, USA; Corresponding author. 5323 Harry Hines Blvd, Dallas, TX, 75390, USA.Department of Pathology. University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, TX, 75390, Dallas, USADepartment of Ophthalmology. University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, TX, 75390, Dallas, USADepartment of Ophthalmology. University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, TX, 75390, Dallas, USADepartment of Ophthalmology. University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, TX, 75390, Dallas, USA; Department of Pathology. University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, TX, 75390, Dallas, USAPurpose: We report a case with over 6 years of follow-up for well-differentiated liposarcoma or atypical lipomatous tumor (WDL/ALT). Observations: Over a 6-year time course, a patient with a recurrent right orbital mass was biopsied/debulked four times. It was not until the fourth biopsy that a diagnosis of WDL/ALT was obtained. Throughout the time course, the patient maintained good vision and there has been no evidence of dedifferentiation or metastasis thus far. Conclusions: The diagnosis of WDL/ALT sound be considered in the cases of a recurrent orbit mass when pathology continually shows nonspecific fibrofatty tissue with chronic inflammatory changes.http://www.sciencedirect.com/science/article/pii/S2451993622003486LiposarcomaProptosisOrbital massOculoplasticOcular pathology
spellingShingle Frank Mei
Lin He
Parsha Forouzan
Ronald Mancini
Robert Nick Hogan
Recurrent primary orbital well-differentiated liposarcoma /atypical lipomatous tumor: A rare case report with six-year follow-up
American Journal of Ophthalmology Case Reports
Liposarcoma
Proptosis
Orbital mass
Oculoplastic
Ocular pathology
title Recurrent primary orbital well-differentiated liposarcoma /atypical lipomatous tumor: A rare case report with six-year follow-up
title_full Recurrent primary orbital well-differentiated liposarcoma /atypical lipomatous tumor: A rare case report with six-year follow-up
title_fullStr Recurrent primary orbital well-differentiated liposarcoma /atypical lipomatous tumor: A rare case report with six-year follow-up
title_full_unstemmed Recurrent primary orbital well-differentiated liposarcoma /atypical lipomatous tumor: A rare case report with six-year follow-up
title_short Recurrent primary orbital well-differentiated liposarcoma /atypical lipomatous tumor: A rare case report with six-year follow-up
title_sort recurrent primary orbital well differentiated liposarcoma atypical lipomatous tumor a rare case report with six year follow up
topic Liposarcoma
Proptosis
Orbital mass
Oculoplastic
Ocular pathology
url http://www.sciencedirect.com/science/article/pii/S2451993622003486
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AT ronaldmancini recurrentprimaryorbitalwelldifferentiatedliposarcomaatypicallipomatoustumorararecasereportwithsixyearfollowup
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