Systematic analysis of MASP-1 serves as a novel immune-related biomarker in sepsis and trauma followed by preliminary experimental validation

Systematic analysis of MASP-1 serves as a novel immune-related biomarker in sepsis and trauma followed by preliminary experimental validation

BackgroundDysregulated immune response in trauma and sepsis leads to the abnormal activation of the complement and coagulation systems. Mannose-binding lectin (MBL)-associated serine protease-1 (MASP-1) activates the lectin pathway of the complement system and mediates proinflammatory and procoagula...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Lina Xian, Shaowen Cheng, Wei Chen, Changhui Zhong, Zhihua Hu, Xiaoyan Deng
التنسيق:	مقال
اللغة:	English
منشور في:	Frontiers Media S.A. 2024-02-01
سلاسل:	Frontiers in Medicine
الموضوعات:	MASP-1 sepsis trauma traumatic sepsis CD8 T cells IL6/JAK/STAT3 signaling
الوصول للمادة أونلاين:	https://www.frontiersin.org/articles/10.3389/fmed.2024.1320811/full

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