Central composite design (CCD) approach to develop HPLC method for caffeine: Application to coffee samples analysis of Jazan region, Saudi Arabia

Central composite design (CCD) approach to develop HPLC method for caffeine: Application to coffee samples analysis of Jazan region, Saudi Arabia

The goal of this study was to use High performance liquid chromatography (HPLC) with an Analytical Quality by Design (AQbD) approach to measure the amount of caffeine in selected coffee samples available in the local Jazan market in Saudi Arabia. The experiment was performed on a Waters HPLC system...

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Bibliographic Details
Main Authors: Asim Najmi, Zia ur Rehman, Khalid Zoghebi, Hassan Ahmed Alhazmi, Mohammed Mofarreh Albratty, Qasem Yahya Hassan Haroobi, Ismail Mohammed Ali Sayram, Mohammed Ahmed Saleh, Waleed Mohammed Ahmed Qaser, Abdulaziz Ali Houssein Qaysi
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Journal of Saudi Chemical Society
Subjects:
Coffee
AQbD
Method development
Validation
ICH guidelines
Online Access:http://www.sciencedirect.com/science/article/pii/S131961032300176X

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