Protective effects of pentoxifylline against chlorine-induced acute lung injury in rats

Protective effects of pentoxifylline against chlorine-induced acute lung injury in rats

Abstract Objective Chlorine is a chemical threat agent that can be harmful to humans. Inhalation of high levels of chlorine can lead to acute lung injury (ALI). Currently, there is no satisfactory treatment, and effective antidote is urgently needed. Pentoxifylline (PTX), a methylxanthine derivative...

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Bibliographic Details
Main Authors: Meng-meng Liu, Jiang-zheng Liu, Chen-qian Zhao, Peng Guo, Zhao Wang, Hao Wu, Weihua Yu, Rui Liu, Chun-xu Hai, Xiao-di Zhang
Format: Article
Language:English
Published: BMC 2023-02-01
Series:BMC Pharmacology and Toxicology
Subjects:
Chlorine
Pentoxifylline
Oxidative stress
Hypoxia
Autophagy
Online Access:https://doi.org/10.1186/s40360-023-00645-2

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