Two-in-one: Combined transcatheter therapy for hypertrophic cardiomyopathy and aortic stenosis
Technical advancements together with robust clinical trial evidence continue to extend the reach of transcatheter therapies. Conditions once considered amenable only to surgery, are now treatable percutaneously offering not only safe outcomes, but in some cases, superior results. Whilst ongoing clin...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-01-01
|
| Series: | IHJ Cardiovascular Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2468600X20300104 |
| _version_ | 1811329180715974656 |
|---|---|
| author | Natalie L. Montarello Ross L. Roberts-Thomson Nicholas J. Montarello Adam J. Nelson Joseph K. Montarello Stephen G. Worthley |
| author_facet | Natalie L. Montarello Ross L. Roberts-Thomson Nicholas J. Montarello Adam J. Nelson Joseph K. Montarello Stephen G. Worthley |
| author_sort | Natalie L. Montarello |
| collection | DOAJ |
| description | Technical advancements together with robust clinical trial evidence continue to extend the reach of transcatheter therapies. Conditions once considered amenable only to surgery, are now treatable percutaneously offering not only safe outcomes, but in some cases, superior results. Whilst ongoing clinical trials will inform which patients are likely to benefit from either approach, safe transcatheter alternatives have been transformative for patients considered unfit for surgery. We present a case from our institution of a septuagenarian with both aortic stenosis and hypertrophic cardiomyopathy deemed unfit for surgery by a porcelain aorta. Alcohol septal ablation (ASA) and transcatheter aortic valve replacement (TAVR) were offered, however in the context of treatment for active malignancy, a previously planned staged intervention had to be performed in a single procedure due to the development of heart failure symptoms. We present the first description of this ‘two-in-one’ intervention and provide background literature review for both ASA and TAVR. |
| first_indexed | 2024-04-13T15:39:16Z |
| format | Article |
| id | doaj.art-d034c783c7ae429eaa7c34e5e05cf223 |
| institution | Directory Open Access Journal |
| issn | 2468-600X |
| language | English |
| last_indexed | 2024-04-13T15:39:16Z |
| publishDate | 2020-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | IHJ Cardiovascular Case Reports |
| spelling | doaj.art-d034c783c7ae429eaa7c34e5e05cf2232022-12-22T02:41:12ZengElsevierIHJ Cardiovascular Case Reports2468-600X2020-01-01411720Two-in-one: Combined transcatheter therapy for hypertrophic cardiomyopathy and aortic stenosisNatalie L. Montarello0Ross L. Roberts-Thomson1Nicholas J. Montarello2Adam J. Nelson3Joseph K. Montarello4Stephen G. Worthley5The Royal Adelaide Hospital, Australia; Corresponding author.The Royal Adelaide Hospital, AustraliaThe Royal Adelaide Hospital, AustraliaThe Royal Adelaide Hospital, AustraliaThe Royal Adelaide Hospital, AustraliaGenesisCare, AustraliaTechnical advancements together with robust clinical trial evidence continue to extend the reach of transcatheter therapies. Conditions once considered amenable only to surgery, are now treatable percutaneously offering not only safe outcomes, but in some cases, superior results. Whilst ongoing clinical trials will inform which patients are likely to benefit from either approach, safe transcatheter alternatives have been transformative for patients considered unfit for surgery. We present a case from our institution of a septuagenarian with both aortic stenosis and hypertrophic cardiomyopathy deemed unfit for surgery by a porcelain aorta. Alcohol septal ablation (ASA) and transcatheter aortic valve replacement (TAVR) were offered, however in the context of treatment for active malignancy, a previously planned staged intervention had to be performed in a single procedure due to the development of heart failure symptoms. We present the first description of this ‘two-in-one’ intervention and provide background literature review for both ASA and TAVR.http://www.sciencedirect.com/science/article/pii/S2468600X20300104Aortic stenosisHypertrophic cardiomyopathyAlcohol septal ablationTranscatheter aortic valve replacement |
| spellingShingle | Natalie L. Montarello Ross L. Roberts-Thomson Nicholas J. Montarello Adam J. Nelson Joseph K. Montarello Stephen G. Worthley Two-in-one: Combined transcatheter therapy for hypertrophic cardiomyopathy and aortic stenosis IHJ Cardiovascular Case Reports Aortic stenosis Hypertrophic cardiomyopathy Alcohol septal ablation Transcatheter aortic valve replacement |
| title | Two-in-one: Combined transcatheter therapy for hypertrophic cardiomyopathy and aortic stenosis |
| title_full | Two-in-one: Combined transcatheter therapy for hypertrophic cardiomyopathy and aortic stenosis |
| title_fullStr | Two-in-one: Combined transcatheter therapy for hypertrophic cardiomyopathy and aortic stenosis |
| title_full_unstemmed | Two-in-one: Combined transcatheter therapy for hypertrophic cardiomyopathy and aortic stenosis |
| title_short | Two-in-one: Combined transcatheter therapy for hypertrophic cardiomyopathy and aortic stenosis |
| title_sort | two in one combined transcatheter therapy for hypertrophic cardiomyopathy and aortic stenosis |
| topic | Aortic stenosis Hypertrophic cardiomyopathy Alcohol septal ablation Transcatheter aortic valve replacement |
| url | http://www.sciencedirect.com/science/article/pii/S2468600X20300104 |
| work_keys_str_mv | AT natalielmontarello twoinonecombinedtranscathetertherapyforhypertrophiccardiomyopathyandaorticstenosis AT rosslrobertsthomson twoinonecombinedtranscathetertherapyforhypertrophiccardiomyopathyandaorticstenosis AT nicholasjmontarello twoinonecombinedtranscathetertherapyforhypertrophiccardiomyopathyandaorticstenosis AT adamjnelson twoinonecombinedtranscathetertherapyforhypertrophiccardiomyopathyandaorticstenosis AT josephkmontarello twoinonecombinedtranscathetertherapyforhypertrophiccardiomyopathyandaorticstenosis AT stephengworthley twoinonecombinedtranscathetertherapyforhypertrophiccardiomyopathyandaorticstenosis |