Mutational landscape differences between young-onset and older-onset breast cancer patients

Mutational landscape differences between young-onset and older-onset breast cancer patients

Abstract Background The incidence of breast cancer among young women (aged ≤40 years) has increased in North America and Europe. Fewer than 10% of cases among young women are attributable to inherited BRCA1 or BRCA2 mutations, suggesting an important role for somatic mutations. This study investigat...

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Bibliographic Details
Main Authors: Nicole E. Mealey, Dylan E. O’Sullivan, Joy Pader, Yibing Ruan, Edwin Wang, May Lynn Quan, Darren R. Brenner
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Cancer
Subjects:
Mutational signatures
Breast cancer
Young women
Genomics
Somatic mutations
Online Access:http://link.springer.com/article/10.1186/s12885-020-6684-z

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http://link.springer.com/article/10.1186/s12885-020-6684-z

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