Gender dimorphism of the cardiac dysfunction in murine sepsis: signalling mechanisms and age-dependency.

Gender dimorphism of the cardiac dysfunction in murine sepsis: signalling mechanisms and age-dependency.

Development of cardiac dysfunction is associated with increased morbidity and mortality in patients with sepsis. Increasing evidence shows that gender determines the degree of inflammatory response of the host and that females tolerate sepsis better than males. It is unknown whether gender affects t...

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Bibliographic Details
Main Authors: Jianmin Chen, Fausto Chiazza, Massimo Collino, Nimesh S A Patel, Sina M Coldewey, Christoph Thiemermann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4063956?pdf=render

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