Femoral Pulse Pressure Variation Is Not Interchangeable with Radial Pulse Pressure Variation during Living Donor Liver Transplantation
The radial artery is commonly used as the site measuring pulse pressure variation (PPV) during surgery. Accurate measurement of circulating blood volume and timely interventions to maintain optimal circulating blood volume is important to deliver sufficient oxygen to tissues and organs. It has not r...
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MDPI AG
2022-08-01
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| Series: | Journal of Personalized Medicine |
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| Online Access: | https://www.mdpi.com/2075-4426/12/8/1352 |
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| author | Doyeon Kim Jin Hee Ahn Sangbin Han Justin Sangwook Ko Mi Sook Gwak Gaab Soo Kim |
| author_facet | Doyeon Kim Jin Hee Ahn Sangbin Han Justin Sangwook Ko Mi Sook Gwak Gaab Soo Kim |
| author_sort | Doyeon Kim |
| collection | DOAJ |
| description | The radial artery is commonly used as the site measuring pulse pressure variation (PPV) during surgery. Accurate measurement of circulating blood volume and timely interventions to maintain optimal circulating blood volume is important to deliver sufficient oxygen to tissues and organs. It has not rather than never studied in patients undergoing liver transplantation whether PPV measured at peripheral sites, such as the radial artery, do represent central PPV for evaluating blood volume. In this retrospective study, 51 liver transplant recipients were enrolled. The two PPVs had been automatically recorded every minute in electrical medical records. A total 1878 pairs of the two PPVs were collected. The interchangeability of PPV measured at the radial and the femoral artery was analyzed by using the Bland–Altman plot, four-quadrant plot, Cohen’s kappa (k), and receiver operating curve. The bias and limits of agreement of the two PPVs were −1.3% and −8.8% to 6.2%, respectively. The percentage error was 75%. The concordance rate was 65%. The Kappa of PPV-radial determining whether PPV-femoral was >13% or ≤13% was 0.64. We found that PPV-radial is not interchangeable with PPV-femoral during liver transplantation. Additionally, PPV-radial failed to reliably track changes of PPV-femoral. Lastly, the clinical decision regarding blood volume status (depletion or not) is significantly different between the two PPVs. Therefore, PPV-femoral may help maintain blood volume circulating to major organs including the newly transplanted liver graft for liver transplant recipients. |
| first_indexed | 2024-03-09T04:14:25Z |
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| issn | 2075-4426 |
| language | English |
| last_indexed | 2024-03-09T04:14:25Z |
| publishDate | 2022-08-01 |
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| series | Journal of Personalized Medicine |
| spelling | doaj.art-d04107bd7f9f422c9f3ae54f38a3767b2023-12-03T13:56:36ZengMDPI AGJournal of Personalized Medicine2075-44262022-08-01128135210.3390/jpm12081352Femoral Pulse Pressure Variation Is Not Interchangeable with Radial Pulse Pressure Variation during Living Donor Liver TransplantationDoyeon Kim0Jin Hee Ahn1Sangbin Han2Justin Sangwook Ko3Mi Sook Gwak4Gaab Soo Kim5Department of Anesthesiology and Pain Medicine, Inha University Hospital, Inha University School of Medicine, Incheon 22332, KoreaDepartment of Anesthesiology and Pain Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul 03181, KoreaDepartment of Anesthesiology and Pain Medicine, Samsung Medical Centre, Sungkyunkwan University School of Medicine, Seoul 06351, KoreaDepartment of Anesthesiology and Pain Medicine, Samsung Medical Centre, Sungkyunkwan University School of Medicine, Seoul 06351, KoreaDepartment of Anesthesiology and Pain Medicine, Samsung Medical Centre, Sungkyunkwan University School of Medicine, Seoul 06351, KoreaDepartment of Anesthesiology and Pain Medicine, Samsung Medical Centre, Sungkyunkwan University School of Medicine, Seoul 06351, KoreaThe radial artery is commonly used as the site measuring pulse pressure variation (PPV) during surgery. Accurate measurement of circulating blood volume and timely interventions to maintain optimal circulating blood volume is important to deliver sufficient oxygen to tissues and organs. It has not rather than never studied in patients undergoing liver transplantation whether PPV measured at peripheral sites, such as the radial artery, do represent central PPV for evaluating blood volume. In this retrospective study, 51 liver transplant recipients were enrolled. The two PPVs had been automatically recorded every minute in electrical medical records. A total 1878 pairs of the two PPVs were collected. The interchangeability of PPV measured at the radial and the femoral artery was analyzed by using the Bland–Altman plot, four-quadrant plot, Cohen’s kappa (k), and receiver operating curve. The bias and limits of agreement of the two PPVs were −1.3% and −8.8% to 6.2%, respectively. The percentage error was 75%. The concordance rate was 65%. The Kappa of PPV-radial determining whether PPV-femoral was >13% or ≤13% was 0.64. We found that PPV-radial is not interchangeable with PPV-femoral during liver transplantation. Additionally, PPV-radial failed to reliably track changes of PPV-femoral. Lastly, the clinical decision regarding blood volume status (depletion or not) is significantly different between the two PPVs. Therefore, PPV-femoral may help maintain blood volume circulating to major organs including the newly transplanted liver graft for liver transplant recipients.https://www.mdpi.com/2075-4426/12/8/1352cirrhosisend-stage liver diseasehyperdynamic circulationvascular resistancevascular complianceBland–Altman plot |
| spellingShingle | Doyeon Kim Jin Hee Ahn Sangbin Han Justin Sangwook Ko Mi Sook Gwak Gaab Soo Kim Femoral Pulse Pressure Variation Is Not Interchangeable with Radial Pulse Pressure Variation during Living Donor Liver Transplantation Journal of Personalized Medicine cirrhosis end-stage liver disease hyperdynamic circulation vascular resistance vascular compliance Bland–Altman plot |
| title | Femoral Pulse Pressure Variation Is Not Interchangeable with Radial Pulse Pressure Variation during Living Donor Liver Transplantation |
| title_full | Femoral Pulse Pressure Variation Is Not Interchangeable with Radial Pulse Pressure Variation during Living Donor Liver Transplantation |
| title_fullStr | Femoral Pulse Pressure Variation Is Not Interchangeable with Radial Pulse Pressure Variation during Living Donor Liver Transplantation |
| title_full_unstemmed | Femoral Pulse Pressure Variation Is Not Interchangeable with Radial Pulse Pressure Variation during Living Donor Liver Transplantation |
| title_short | Femoral Pulse Pressure Variation Is Not Interchangeable with Radial Pulse Pressure Variation during Living Donor Liver Transplantation |
| title_sort | femoral pulse pressure variation is not interchangeable with radial pulse pressure variation during living donor liver transplantation |
| topic | cirrhosis end-stage liver disease hyperdynamic circulation vascular resistance vascular compliance Bland–Altman plot |
| url | https://www.mdpi.com/2075-4426/12/8/1352 |
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