Development of the non-occupational post-exposure prophylaxis (NPEP) knowledge scale among Chinese men who have sex with men
Abstract Background Nonoccupational post-exposure prophylaxis (NPEP) is a short course of medication taken to reduce the likelihood of acquiring human immunodeficiency virus (HIV) infection upon exposure. A review of the literature demonstrates an urgent need for an empirically validated instrument...
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| Format: | Article |
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BMC
2023-07-01
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| Series: | BMC Public Health |
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| Online Access: | https://doi.org/10.1186/s12889-023-16206-5 |
| _version_ | 1797778663105626112 |
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| author | Haochu Li Ran Wei Traci L. Weinstein Eunsook Kim Angela J. Jacques-Tiura Xiaofu Ning Wei Ma |
| author_facet | Haochu Li Ran Wei Traci L. Weinstein Eunsook Kim Angela J. Jacques-Tiura Xiaofu Ning Wei Ma |
| author_sort | Haochu Li |
| collection | DOAJ |
| description | Abstract Background Nonoccupational post-exposure prophylaxis (NPEP) is a short course of medication taken to reduce the likelihood of acquiring human immunodeficiency virus (HIV) infection upon exposure. A review of the literature demonstrates an urgent need for an empirically validated instrument that measures detailed knowledge of NPEP among the key population of men who have sex with men (MSM). Methods Semi-structured interviews, focus groups, and a cross-sectional survey with a sample of 419 MSM was conducted in 2018 in China to develop and psychometrically evaluate the new instrument, the NPEP Knowledge Scale. Exploratory and confirmatory factor analyses, differential item functioning analyses, and structural equation modeling were conducted using Mplus 7.4. Results The NPEP Knowledge Scale demonstrated excellent reliability and validity. Cronbach’s alpha was 0.903. The range of item R2 were 0.527–0.969, p’s < 0.001. Model estimated inter-item correlations ranged between 0.534 and 0.968. In addition, HIV knowledge, NPEP use, and NPEP knowledge were all significantly correlated. Conclusions The NPEP Knowledge Scale is suitable for research, program evaluation, and clinical and community services that require using NPEP to minimize the ever-present risk of new HIV infections. |
| first_indexed | 2024-03-12T23:20:42Z |
| format | Article |
| id | doaj.art-d044c144ab844d77b0c0737aa096cd8c |
| institution | Directory Open Access Journal |
| issn | 1471-2458 |
| language | English |
| last_indexed | 2024-03-12T23:20:42Z |
| publishDate | 2023-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Public Health |
| spelling | doaj.art-d044c144ab844d77b0c0737aa096cd8c2023-07-16T11:30:22ZengBMCBMC Public Health1471-24582023-07-012311910.1186/s12889-023-16206-5Development of the non-occupational post-exposure prophylaxis (NPEP) knowledge scale among Chinese men who have sex with menHaochu Li0Ran Wei1Traci L. Weinstein2Eunsook Kim3Angela J. Jacques-Tiura4Xiaofu Ning5Wei Ma6Department of Epidemiology, School of Public Health, Shandong UniversityDepartment of Epidemiology, School of Public Health, Shandong UniversityDepartment of Psychology, Rhode Island CollegeDepartment of Educational and Psychological Studies, University of South FloridaDepartment of Family Medicine and Public Health Sciences, Wayne State UniversitySchool of Pharmaceutical Sciences, Peking UniversityDepartment of Epidemiology, School of Public Health, Shandong UniversityAbstract Background Nonoccupational post-exposure prophylaxis (NPEP) is a short course of medication taken to reduce the likelihood of acquiring human immunodeficiency virus (HIV) infection upon exposure. A review of the literature demonstrates an urgent need for an empirically validated instrument that measures detailed knowledge of NPEP among the key population of men who have sex with men (MSM). Methods Semi-structured interviews, focus groups, and a cross-sectional survey with a sample of 419 MSM was conducted in 2018 in China to develop and psychometrically evaluate the new instrument, the NPEP Knowledge Scale. Exploratory and confirmatory factor analyses, differential item functioning analyses, and structural equation modeling were conducted using Mplus 7.4. Results The NPEP Knowledge Scale demonstrated excellent reliability and validity. Cronbach’s alpha was 0.903. The range of item R2 were 0.527–0.969, p’s < 0.001. Model estimated inter-item correlations ranged between 0.534 and 0.968. In addition, HIV knowledge, NPEP use, and NPEP knowledge were all significantly correlated. Conclusions The NPEP Knowledge Scale is suitable for research, program evaluation, and clinical and community services that require using NPEP to minimize the ever-present risk of new HIV infections.https://doi.org/10.1186/s12889-023-16206-5Nonoccupational post-exposure Prophylaxis (NPEP)PsychometricsStructural equation modelingMen who have sex with menChina |
| spellingShingle | Haochu Li Ran Wei Traci L. Weinstein Eunsook Kim Angela J. Jacques-Tiura Xiaofu Ning Wei Ma Development of the non-occupational post-exposure prophylaxis (NPEP) knowledge scale among Chinese men who have sex with men BMC Public Health Nonoccupational post-exposure Prophylaxis (NPEP) Psychometrics Structural equation modeling Men who have sex with men China |
| title | Development of the non-occupational post-exposure prophylaxis (NPEP) knowledge scale among Chinese men who have sex with men |
| title_full | Development of the non-occupational post-exposure prophylaxis (NPEP) knowledge scale among Chinese men who have sex with men |
| title_fullStr | Development of the non-occupational post-exposure prophylaxis (NPEP) knowledge scale among Chinese men who have sex with men |
| title_full_unstemmed | Development of the non-occupational post-exposure prophylaxis (NPEP) knowledge scale among Chinese men who have sex with men |
| title_short | Development of the non-occupational post-exposure prophylaxis (NPEP) knowledge scale among Chinese men who have sex with men |
| title_sort | development of the non occupational post exposure prophylaxis npep knowledge scale among chinese men who have sex with men |
| topic | Nonoccupational post-exposure Prophylaxis (NPEP) Psychometrics Structural equation modeling Men who have sex with men China |
| url | https://doi.org/10.1186/s12889-023-16206-5 |
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