Effectiveness of long-lasting insecticidal nets in prevention of malaria among individuals visiting health centres in Ziway-Dugda District, Ethiopia: matched case–control study
Abstract Background Malaria is a major health problem in Ethiopia. Sleeping under long-lasting insecticidal nets (LLINs) is its major control strategy. Despite high LLINs use (84%) in Ziway-Dugda District, malaria remained a public health problem, raising concern on its effectiveness. Understanding...
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| Format: | Article |
| Language: | English |
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BMC
2021-07-01
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| Series: | Malaria Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12936-021-03833-9 |
| _version_ | 1818956807442268160 |
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| author | Mesfin Kelkile Wubishet Gebretsadik Berhe Alefech Adissu Mesfin Segni Tafa |
| author_facet | Mesfin Kelkile Wubishet Gebretsadik Berhe Alefech Adissu Mesfin Segni Tafa |
| author_sort | Mesfin Kelkile Wubishet |
| collection | DOAJ |
| description | Abstract Background Malaria is a major health problem in Ethiopia. Sleeping under long-lasting insecticidal nets (LLINs) is its major control strategy. Despite high LLINs use (84%) in Ziway-Dugda District, malaria remained a public health problem, raising concern on its effectiveness. Understanding the effectiveness of malaria control interventions is vital. This study evaluated the effectiveness of LLINs and determinants of malaria in Ziway-Dugda District, Arsi Zone Ethiopia. Methods A matched case–control study was conducted among 284 study participants (71 cases and 213 controls) in Ziway-Dugda District, Arsi Zone, Ethiopia from March to May, 2017. Three health centers were selected randomly, and enrolled individuals newly diagnosed for malaria proportionally. Cases and controls were individuals testing positive and negative for malaria using rapid diagnostic tests. Each case was matched to three controls using the age of (5 years), gender and village of residence. The information was collected using pre-tested structured questionnaires through face to face interviews and observation. Data were entered into Epi-Info version 3.5, and analysed using Stata version-12. Conditional logistic regression was performed, and odds of LLINs use were compared using matched Adjusted Odds Ratio (AOR), 95% confidence interval (CI) and p-value of < 0.05. Results One hundred twenty-three (61.2%) of the controls and 22 (32.8%) of cases had regularly slept under LLINs in the past two weeks. Using multivariate analysis, sleeping under LLINs for the past two weeks (AOR = 0.23, 95%CI = 0.11–0.45); living in houses sprayed with indoor residual spray (IRS) (AOR = 0.23, 95%CI: 0.10–0.52); and staying late outdoors at night in the past two-weeks (AOR = 2.99, 95%CI = 1.44–6.19) were determinant factors. Conclusions Sleeping under LLINs is effective for malaria prevention in the district. IRS and staying late outdoors at night were determinants of malaria. It is recommended to increase attention on strengthening LLINs use and IRS in the area. |
| first_indexed | 2024-12-20T10:59:49Z |
| format | Article |
| id | doaj.art-d0476903d918443ea9893e97b69a1149 |
| institution | Directory Open Access Journal |
| issn | 1475-2875 |
| language | English |
| last_indexed | 2024-12-20T10:59:49Z |
| publishDate | 2021-07-01 |
| publisher | BMC |
| record_format | Article |
| series | Malaria Journal |
| spelling | doaj.art-d0476903d918443ea9893e97b69a11492022-12-21T19:43:03ZengBMCMalaria Journal1475-28752021-07-0120111510.1186/s12936-021-03833-9Effectiveness of long-lasting insecticidal nets in prevention of malaria among individuals visiting health centres in Ziway-Dugda District, Ethiopia: matched case–control studyMesfin Kelkile Wubishet0Gebretsadik Berhe1Alefech Adissu2Mesfin Segni Tafa3Ethiopian Field Epidemiology and Laboratory Training Programme (EFELTP), Arsi Zonal Health DepartmentSchool of Public Health, College of Health Sciences, Mekelle UniversityEthiopian Federal Ministry of HealthEpidemiology At Arsi Universities, Department of Public Health, College of Health ScienceAbstract Background Malaria is a major health problem in Ethiopia. Sleeping under long-lasting insecticidal nets (LLINs) is its major control strategy. Despite high LLINs use (84%) in Ziway-Dugda District, malaria remained a public health problem, raising concern on its effectiveness. Understanding the effectiveness of malaria control interventions is vital. This study evaluated the effectiveness of LLINs and determinants of malaria in Ziway-Dugda District, Arsi Zone Ethiopia. Methods A matched case–control study was conducted among 284 study participants (71 cases and 213 controls) in Ziway-Dugda District, Arsi Zone, Ethiopia from March to May, 2017. Three health centers were selected randomly, and enrolled individuals newly diagnosed for malaria proportionally. Cases and controls were individuals testing positive and negative for malaria using rapid diagnostic tests. Each case was matched to three controls using the age of (5 years), gender and village of residence. The information was collected using pre-tested structured questionnaires through face to face interviews and observation. Data were entered into Epi-Info version 3.5, and analysed using Stata version-12. Conditional logistic regression was performed, and odds of LLINs use were compared using matched Adjusted Odds Ratio (AOR), 95% confidence interval (CI) and p-value of < 0.05. Results One hundred twenty-three (61.2%) of the controls and 22 (32.8%) of cases had regularly slept under LLINs in the past two weeks. Using multivariate analysis, sleeping under LLINs for the past two weeks (AOR = 0.23, 95%CI = 0.11–0.45); living in houses sprayed with indoor residual spray (IRS) (AOR = 0.23, 95%CI: 0.10–0.52); and staying late outdoors at night in the past two-weeks (AOR = 2.99, 95%CI = 1.44–6.19) were determinant factors. Conclusions Sleeping under LLINs is effective for malaria prevention in the district. IRS and staying late outdoors at night were determinants of malaria. It is recommended to increase attention on strengthening LLINs use and IRS in the area.https://doi.org/10.1186/s12936-021-03833-9EffectivenessMalariaMatched case–controlLong-lasting insecticide-treated netsZiway-Dugda districtEthiopia |
| spellingShingle | Mesfin Kelkile Wubishet Gebretsadik Berhe Alefech Adissu Mesfin Segni Tafa Effectiveness of long-lasting insecticidal nets in prevention of malaria among individuals visiting health centres in Ziway-Dugda District, Ethiopia: matched case–control study Malaria Journal Effectiveness Malaria Matched case–control Long-lasting insecticide-treated nets Ziway-Dugda district Ethiopia |
| title | Effectiveness of long-lasting insecticidal nets in prevention of malaria among individuals visiting health centres in Ziway-Dugda District, Ethiopia: matched case–control study |
| title_full | Effectiveness of long-lasting insecticidal nets in prevention of malaria among individuals visiting health centres in Ziway-Dugda District, Ethiopia: matched case–control study |
| title_fullStr | Effectiveness of long-lasting insecticidal nets in prevention of malaria among individuals visiting health centres in Ziway-Dugda District, Ethiopia: matched case–control study |
| title_full_unstemmed | Effectiveness of long-lasting insecticidal nets in prevention of malaria among individuals visiting health centres in Ziway-Dugda District, Ethiopia: matched case–control study |
| title_short | Effectiveness of long-lasting insecticidal nets in prevention of malaria among individuals visiting health centres in Ziway-Dugda District, Ethiopia: matched case–control study |
| title_sort | effectiveness of long lasting insecticidal nets in prevention of malaria among individuals visiting health centres in ziway dugda district ethiopia matched case control study |
| topic | Effectiveness Malaria Matched case–control Long-lasting insecticide-treated nets Ziway-Dugda district Ethiopia |
| url | https://doi.org/10.1186/s12936-021-03833-9 |
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