Unilateral Dyshidrosiform Pemphigus Vulgaris
Pemphigus vulgaris is an autoimmune disease characterized by fluid-filled blisters over body and mucosal surfaces. Localized pemphigus is a rare presentation of the disease. There are few reports of localized pemphigus in literature presenting as esophageal involvement, recurrent paronychia, conjunc...
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2020-06-01
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Series: | Annals of the National Academy of Medical Sciences (India) |
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Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1713184 |
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author | Manju Daroach Dipankar De Sanjeev Handa Rahul Mahajan Vikarn Vishwajeet Uma N. Saikia |
author_facet | Manju Daroach Dipankar De Sanjeev Handa Rahul Mahajan Vikarn Vishwajeet Uma N. Saikia |
author_sort | Manju Daroach |
collection | DOAJ |
description | Pemphigus vulgaris is an autoimmune disease characterized by fluid-filled blisters over body and mucosal surfaces. Localized pemphigus is a rare presentation of the disease. There are few reports of localized pemphigus in literature presenting as esophageal involvement, recurrent paronychia, conjunctival mass, foot ulcers, discoloration of toes with hyperkeratotic skin lesions, verrucous lesions, and dyshidrosiform pemphigus vulgaris. We present a case of dyshidrosiform pemphigus involving a foot following trauma. Histopathology and direct immunofluorescence confirmed our diagnosis. In our patient, the disease started as localized dyshidrosiform pemphigus and later became generalized. This unusual presentation led to a delay in diagnosis and proper treatment in this patient. Physicians should be aware of such rare presentations to aid in the timely diagnosis and management of such patients. |
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institution | Directory Open Access Journal |
issn | 0379-038X 2454-5635 |
language | English |
last_indexed | 2024-12-17T01:51:54Z |
publishDate | 2020-06-01 |
publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
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series | Annals of the National Academy of Medical Sciences (India) |
spelling | doaj.art-d049b7f8ea1540508149f7ac150953ff2022-12-21T22:08:02ZengThieme Medical and Scientific Publishers Pvt. Ltd.Annals of the National Academy of Medical Sciences (India)0379-038X2454-56352020-06-01560423123310.1055/s-0040-1713184Unilateral Dyshidrosiform Pemphigus VulgarisManju Daroach0Dipankar De1Sanjeev Handa2Rahul Mahajan3Vikarn Vishwajeet4Uma N. Saikia5Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, IndiaDepartment of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, IndiaDepartment of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, IndiaDepartment of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, IndiaDepartment of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, IndiaDepartment of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, IndiaPemphigus vulgaris is an autoimmune disease characterized by fluid-filled blisters over body and mucosal surfaces. Localized pemphigus is a rare presentation of the disease. There are few reports of localized pemphigus in literature presenting as esophageal involvement, recurrent paronychia, conjunctival mass, foot ulcers, discoloration of toes with hyperkeratotic skin lesions, verrucous lesions, and dyshidrosiform pemphigus vulgaris. We present a case of dyshidrosiform pemphigus involving a foot following trauma. Histopathology and direct immunofluorescence confirmed our diagnosis. In our patient, the disease started as localized dyshidrosiform pemphigus and later became generalized. This unusual presentation led to a delay in diagnosis and proper treatment in this patient. Physicians should be aware of such rare presentations to aid in the timely diagnosis and management of such patients.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1713184pemphigus vulgarisdyshidrosiformunilateral |
spellingShingle | Manju Daroach Dipankar De Sanjeev Handa Rahul Mahajan Vikarn Vishwajeet Uma N. Saikia Unilateral Dyshidrosiform Pemphigus Vulgaris Annals of the National Academy of Medical Sciences (India) pemphigus vulgaris dyshidrosiform unilateral |
title | Unilateral Dyshidrosiform Pemphigus Vulgaris |
title_full | Unilateral Dyshidrosiform Pemphigus Vulgaris |
title_fullStr | Unilateral Dyshidrosiform Pemphigus Vulgaris |
title_full_unstemmed | Unilateral Dyshidrosiform Pemphigus Vulgaris |
title_short | Unilateral Dyshidrosiform Pemphigus Vulgaris |
title_sort | unilateral dyshidrosiform pemphigus vulgaris |
topic | pemphigus vulgaris dyshidrosiform unilateral |
url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1713184 |
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