Lateral habenula glutamatergic neurons projecting to the dorsal raphe nucleus promote aggressive arousal in mice
The dorsal raphe nucleus (DRN) is known to modulate aggressive behaviour in rodents. Here the authors show that glutamatergic projections from the lateral habenula to DRN modulate aggression between male mice.
| Main Authors: | , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-07-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-31728-z |
| _version_ | 1818509777216471040 |
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| author | Aki Takahashi Romain Durand-de Cuttoli Meghan E. Flanigan Emi Hasegawa Tomomi Tsunematsu Hossein Aleyasin Yoan Cherasse Ken Miya Takuya Okada Kazuko Keino-Masu Koshiro Mitsui Long Li Vishwendra Patel Robert D. Blitzer Michael Lazarus Kenji F. Tanaka Akihiro Yamanaka Takeshi Sakurai Sonoko Ogawa Scott J. Russo |
| author_facet | Aki Takahashi Romain Durand-de Cuttoli Meghan E. Flanigan Emi Hasegawa Tomomi Tsunematsu Hossein Aleyasin Yoan Cherasse Ken Miya Takuya Okada Kazuko Keino-Masu Koshiro Mitsui Long Li Vishwendra Patel Robert D. Blitzer Michael Lazarus Kenji F. Tanaka Akihiro Yamanaka Takeshi Sakurai Sonoko Ogawa Scott J. Russo |
| author_sort | Aki Takahashi |
| collection | DOAJ |
| description | The dorsal raphe nucleus (DRN) is known to modulate aggressive behaviour in rodents. Here the authors show that glutamatergic projections from the lateral habenula to DRN modulate aggression between male mice. |
| first_indexed | 2024-12-10T22:50:06Z |
| format | Article |
| id | doaj.art-d04c343a8d9249c48d96d5f41f361fc1 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-10T22:50:06Z |
| publishDate | 2022-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-d04c343a8d9249c48d96d5f41f361fc12022-12-22T01:30:27ZengNature PortfolioNature Communications2041-17232022-07-0113111810.1038/s41467-022-31728-zLateral habenula glutamatergic neurons projecting to the dorsal raphe nucleus promote aggressive arousal in miceAki Takahashi0Romain Durand-de Cuttoli1Meghan E. Flanigan2Emi Hasegawa3Tomomi Tsunematsu4Hossein Aleyasin5Yoan Cherasse6Ken Miya7Takuya Okada8Kazuko Keino-Masu9Koshiro Mitsui10Long Li11Vishwendra Patel12Robert D. Blitzer13Michael Lazarus14Kenji F. Tanaka15Akihiro Yamanaka16Takeshi Sakurai17Sonoko Ogawa18Scott J. Russo19Laboratory of Behavioral Neurobiology, Faculty of Human Sciences, University of TsukubaNash Family Department of Neuroscience and Brain & Body Research Center, Icahn School of Medicine at Mount SinaiNash Family Department of Neuroscience and Brain & Body Research Center, Icahn School of Medicine at Mount SinaiDepartment of Molecular Behavioral Physiology, Faculty of Medicine, University of TsukubaSuper-network Brain Physiology, Graduate School of Life Sciences, Tohoku UniversityNash Family Department of Neuroscience and Brain & Body Research Center, Icahn School of Medicine at Mount SinaiInternational Institute for Integrative Sleep Medicine (WPI-IIIS), University of TsukubaDepartment of Molecular Neurobiology, Faculty of Medicine, University of TsukubaDepartment of Molecular Neurobiology, Faculty of Medicine, University of TsukubaDepartment of Molecular Neurobiology, Faculty of Medicine, University of TsukubaLaboratory of Behavioral Neurobiology, Faculty of Human Sciences, University of TsukubaNash Family Department of Neuroscience and Brain & Body Research Center, Icahn School of Medicine at Mount SinaiDepartment of Pharmacological Sciences and Department of Psychiatry, Icahn School of Medicine at Mount SinaiDepartment of Pharmacological Sciences and Department of Psychiatry, Icahn School of Medicine at Mount SinaiInternational Institute for Integrative Sleep Medicine (WPI-IIIS), University of TsukubaDepartment of Neuropsychiatry, Keio University School of MedicineDepartment of Neuroscience II, Research Institute of Environmental Medicine, Nagoya UniversityDepartment of Molecular Behavioral Physiology, Faculty of Medicine, University of TsukubaLaboratory of Behavioral Neuroendocrinology, Faculty of Human Sciences, University of TsukubaNash Family Department of Neuroscience and Brain & Body Research Center, Icahn School of Medicine at Mount SinaiThe dorsal raphe nucleus (DRN) is known to modulate aggressive behaviour in rodents. Here the authors show that glutamatergic projections from the lateral habenula to DRN modulate aggression between male mice.https://doi.org/10.1038/s41467-022-31728-z |
| spellingShingle | Aki Takahashi Romain Durand-de Cuttoli Meghan E. Flanigan Emi Hasegawa Tomomi Tsunematsu Hossein Aleyasin Yoan Cherasse Ken Miya Takuya Okada Kazuko Keino-Masu Koshiro Mitsui Long Li Vishwendra Patel Robert D. Blitzer Michael Lazarus Kenji F. Tanaka Akihiro Yamanaka Takeshi Sakurai Sonoko Ogawa Scott J. Russo Lateral habenula glutamatergic neurons projecting to the dorsal raphe nucleus promote aggressive arousal in mice Nature Communications |
| title | Lateral habenula glutamatergic neurons projecting to the dorsal raphe nucleus promote aggressive arousal in mice |
| title_full | Lateral habenula glutamatergic neurons projecting to the dorsal raphe nucleus promote aggressive arousal in mice |
| title_fullStr | Lateral habenula glutamatergic neurons projecting to the dorsal raphe nucleus promote aggressive arousal in mice |
| title_full_unstemmed | Lateral habenula glutamatergic neurons projecting to the dorsal raphe nucleus promote aggressive arousal in mice |
| title_short | Lateral habenula glutamatergic neurons projecting to the dorsal raphe nucleus promote aggressive arousal in mice |
| title_sort | lateral habenula glutamatergic neurons projecting to the dorsal raphe nucleus promote aggressive arousal in mice |
| url | https://doi.org/10.1038/s41467-022-31728-z |
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