A nanobody-based molecular toolkit for ubiquitin–proteasome system explores the main role of survivin subcellular localization

A nanobody-based molecular toolkit for ubiquitin–proteasome system explores the main role of survivin subcellular localization

Targeted protein degradation is a powerful tool for determining the function of specific proteins nowadays. Survivin is the smallest member of the inhibitor of the apoptosis protein (IAP) family. It exists in the cytoplasm and nucleus of cells, but the exact function of survivin in different subcell...

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Bibliographic Details
Main Authors: Hui Miao, Chang Liu, Hao Ouyang, Peiwen Zhang, Yuping Liu, Chen Zhang, Changping Deng, Yunhui Fu, Jinping Niu, Wenyun Zheng, Fang You, Yi Yang, Xingyuan Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
survivin subcellular function
nanobody targeted
TRIM21
apoptosis and cell cycle
anti-cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.952237/full

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