Influence of metal of the applicator on the dose distribution during brachytherapy.

This study explores how the metal materials of the applicator influence the dose distribution when performing brachytherapy for cervical cancer. A pinpoint ionization chamber, Monte Carlo code MCNPX, and treatment planning system are used to evaluate the dose distribution for a single Ir-192 source...

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Main Authors: Chin-Hui Wu, An-Cheng Shiau, Yi-Jen Liao, Hsin-Yu Lin, Yen-Wan Hsueh Liu, Shih-Ming Hsu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4136780?pdf=render
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author Chin-Hui Wu
An-Cheng Shiau
Yi-Jen Liao
Hsin-Yu Lin
Yen-Wan Hsueh Liu
Shih-Ming Hsu
author_facet Chin-Hui Wu
An-Cheng Shiau
Yi-Jen Liao
Hsin-Yu Lin
Yen-Wan Hsueh Liu
Shih-Ming Hsu
author_sort Chin-Hui Wu
collection DOAJ
description This study explores how the metal materials of the applicator influence the dose distribution when performing brachytherapy for cervical cancer. A pinpoint ionization chamber, Monte Carlo code MCNPX, and treatment planning system are used to evaluate the dose distribution for a single Ir-192 source positioned in the tandem and ovoid. For dose distribution in water with the presence of the tandem, differences among measurement, MCNPX calculation and treatment planning system results are <5%. For dose distribution in water with the presence of the ovoid, the MCNPX result agrees with the measurement. But the doses calculated from treatment planning system are overestimated by up to a factor of 4. This is due to the shielding effect of the metal materials in the applicator not being considered in the treatment planning system. This result suggests that the treatment planning system should take into account corrections for the metal materials of the applicator in order to improve the accuracy of the radiation dose delivered.
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spelling doaj.art-d04df912fbbf4210b3a7bef598e3ec272022-12-22T02:27:23ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0198e10483110.1371/journal.pone.0104831Influence of metal of the applicator on the dose distribution during brachytherapy.Chin-Hui WuAn-Cheng ShiauYi-Jen LiaoHsin-Yu LinYen-Wan Hsueh LiuShih-Ming HsuThis study explores how the metal materials of the applicator influence the dose distribution when performing brachytherapy for cervical cancer. A pinpoint ionization chamber, Monte Carlo code MCNPX, and treatment planning system are used to evaluate the dose distribution for a single Ir-192 source positioned in the tandem and ovoid. For dose distribution in water with the presence of the tandem, differences among measurement, MCNPX calculation and treatment planning system results are <5%. For dose distribution in water with the presence of the ovoid, the MCNPX result agrees with the measurement. But the doses calculated from treatment planning system are overestimated by up to a factor of 4. This is due to the shielding effect of the metal materials in the applicator not being considered in the treatment planning system. This result suggests that the treatment planning system should take into account corrections for the metal materials of the applicator in order to improve the accuracy of the radiation dose delivered.http://europepmc.org/articles/PMC4136780?pdf=render
spellingShingle Chin-Hui Wu
An-Cheng Shiau
Yi-Jen Liao
Hsin-Yu Lin
Yen-Wan Hsueh Liu
Shih-Ming Hsu
Influence of metal of the applicator on the dose distribution during brachytherapy.
PLoS ONE
title Influence of metal of the applicator on the dose distribution during brachytherapy.
title_full Influence of metal of the applicator on the dose distribution during brachytherapy.
title_fullStr Influence of metal of the applicator on the dose distribution during brachytherapy.
title_full_unstemmed Influence of metal of the applicator on the dose distribution during brachytherapy.
title_short Influence of metal of the applicator on the dose distribution during brachytherapy.
title_sort influence of metal of the applicator on the dose distribution during brachytherapy
url http://europepmc.org/articles/PMC4136780?pdf=render
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