Effectiveness of surgical and combined treatment of supratentorial primitive neuroectodermal tumors in children
Introduction. The results of use of modern methods of treatment of malignant embryonic brain tumors — supratentorial primitive neuroectodermal tumors (sPNET) are given.Materials and methods. The retrospective analysis of treatment results of 73 children with primitive brain sPNET in a per...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Romodanov Neurosurgery Institute
2014-09-01
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| Series: | Ukrainian Neurosurgical Journal |
| Online Access: | https://theunj.org/article/view/47486 |
| Summary: | Introduction. The results of use of modern methods of treatment of malignant embryonic brain tumors — supratentorial primitive neuroectodermal tumors (sPNET) are given.Materials and methods. The retrospective analysis of treatment results of 73 children with primitive brain sPNET in a period 1995–2011 was done. Combined methods of treatment were used — surgery, radiotherapy and chemotherapy.Results. The study results demonstrate the need for aggressive therapy at such malignant tumors. After surgery death rate was 5.5%, survival rate in average — 31.2 months. Surgery radicalism, application of radiotherapy and chemotherapy affect the survival rate and quality of life of the patient.Conclusion. Patients older than 3 years at whom according to treatment protocols at sPNEO radiotherapy can be used, as well as a comprehensive approach to treatment are positive predictors of survival and quality of life. |
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| ISSN: | 2663-9084 2663-9092 |