Metastatic Brain Tumors
Metastatic tumor is secondary spread to the central nervous system of primer systemic cancers originating from tissues other than the central nervous system. In adults; there are metastases respectively from lungs, breasts, malign melanoma, renal cell carcinoma, colon and thyroid cancers. 30-60% of...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Cukurova University
2014-04-01
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| Series: | Çukurova Üniversitesi Tıp Fakültesi Dergisi |
| Subjects: | |
| Online Access: | http://www.scopemed.org/fulltextpdf.php?mno=46261 |
| _version_ | 1797912322858024960 |
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| author | Ersin Haciyakupoglu Kadir Oktay Semih Kivanc Olguner Dervis Mansuri Yilmaz Sebahattin Haciyakupoglu |
| author_facet | Ersin Haciyakupoglu Kadir Oktay Semih Kivanc Olguner Dervis Mansuri Yilmaz Sebahattin Haciyakupoglu |
| author_sort | Ersin Haciyakupoglu |
| collection | DOAJ |
| description | Metastatic tumor is secondary spread to the central nervous system of primer systemic cancers originating from tissues other than the central nervous system. In adults; there are metastases respectively from lungs, breasts, malign melanoma, renal cell carcinoma, colon and thyroid cancers. 30-60% of lung cancers metastasis to the brain. In children there are quite a few cerebral metastases. Most commonly leukemia, lymphoma, osteogenic sarcoma, rhabdomyosarcoma and germ cell tumors metastasis to the brain. %50 of malign melanoma, lung, breast and colon cancers intend to make multipl metastases but renal cell cancers intend to make solitary metastasis.While lung cancers metastasis to brain in 6-9 months after the definitive diagnosis, renal cancers in 1 year, colon cancers in 2 years, breast cancers and malign melanoma in 3 years metastasis to brain. In 6% of cases there are cerebral metastasis while there isn’t a symptom of a primary tumor. For treatment corticosteroids, surgery, Radiotherapy(RT), Chemotherapy(CT) and Stereotactic Radiosurgery(SRS) can be implemented. Small cell lung cancers, lymphoma, germ cell tumors are sensitive to RT and CT. Non small cell lung cancers, renal, colon cancers and malign melanoma are radioresistant. The purposes in the surgery of the metastatic brain tumors are; total resection of tumors without neurologic deficits, decreasing the intracranial pressure and decreasing the dose of postoperative radiotherapy.
Key Words: Metastatic brain tumors, Stereotactic radiosurgery, Malign melanoma,
Lung cancers, Renal cell carcinoma, Radiotherapy, Chemotherapy [Cukurova Med J 2014; 39(2.000): 191-202] |
| first_indexed | 2024-04-10T11:54:10Z |
| format | Article |
| id | doaj.art-d0500a58c8874f6bbe9c5edf1368c08f |
| institution | Directory Open Access Journal |
| issn | 0250-5150 |
| language | English |
| last_indexed | 2024-04-10T11:54:10Z |
| publishDate | 2014-04-01 |
| publisher | Cukurova University |
| record_format | Article |
| series | Çukurova Üniversitesi Tıp Fakültesi Dergisi |
| spelling | doaj.art-d0500a58c8874f6bbe9c5edf1368c08f2023-02-15T16:16:59ZengCukurova UniversityÇukurova Üniversitesi Tıp Fakültesi Dergisi0250-51502014-04-0139219120246261Metastatic Brain TumorsErsin Haciyakupoglu0Kadir Oktay1Semih Kivanc Olguner2Dervis Mansuri Yilmaz3Sebahattin Haciyakupoglu4medline hastanesi beyin ve sinir cerrahisi anabilimdali ADANA cukurova universitesi tip fakultesi beyin ve sinir cerrahisi anabilimdali ADANA cukurova universitesi tip fakultesi beyin ve sinir cerrahisi anabilimdali ADANA cukurova universitesi tip fakultesi beyin ve sinir cerrahisi anabilimdali ADANA acibadem hastanesi beyin ve sinir cerrahisi anabilimdali ADANAMetastatic tumor is secondary spread to the central nervous system of primer systemic cancers originating from tissues other than the central nervous system. In adults; there are metastases respectively from lungs, breasts, malign melanoma, renal cell carcinoma, colon and thyroid cancers. 30-60% of lung cancers metastasis to the brain. In children there are quite a few cerebral metastases. Most commonly leukemia, lymphoma, osteogenic sarcoma, rhabdomyosarcoma and germ cell tumors metastasis to the brain. %50 of malign melanoma, lung, breast and colon cancers intend to make multipl metastases but renal cell cancers intend to make solitary metastasis.While lung cancers metastasis to brain in 6-9 months after the definitive diagnosis, renal cancers in 1 year, colon cancers in 2 years, breast cancers and malign melanoma in 3 years metastasis to brain. In 6% of cases there are cerebral metastasis while there isn’t a symptom of a primary tumor. For treatment corticosteroids, surgery, Radiotherapy(RT), Chemotherapy(CT) and Stereotactic Radiosurgery(SRS) can be implemented. Small cell lung cancers, lymphoma, germ cell tumors are sensitive to RT and CT. Non small cell lung cancers, renal, colon cancers and malign melanoma are radioresistant. The purposes in the surgery of the metastatic brain tumors are; total resection of tumors without neurologic deficits, decreasing the intracranial pressure and decreasing the dose of postoperative radiotherapy. Key Words: Metastatic brain tumors, Stereotactic radiosurgery, Malign melanoma, Lung cancers, Renal cell carcinoma, Radiotherapy, Chemotherapy [Cukurova Med J 2014; 39(2.000): 191-202]http://www.scopemed.org/fulltextpdf.php?mno=46261Metastatic brain tumorsStereotactic radiosurgeryMalign melanoma Lung cancersRenal cell carcinomaRadiotherapyChemotherapy |
| spellingShingle | Ersin Haciyakupoglu Kadir Oktay Semih Kivanc Olguner Dervis Mansuri Yilmaz Sebahattin Haciyakupoglu Metastatic Brain Tumors Çukurova Üniversitesi Tıp Fakültesi Dergisi Metastatic brain tumors Stereotactic radiosurgery Malign melanoma Lung cancers Renal cell carcinoma Radiotherapy Chemotherapy |
| title | Metastatic Brain Tumors |
| title_full | Metastatic Brain Tumors |
| title_fullStr | Metastatic Brain Tumors |
| title_full_unstemmed | Metastatic Brain Tumors |
| title_short | Metastatic Brain Tumors |
| title_sort | metastatic brain tumors |
| topic | Metastatic brain tumors Stereotactic radiosurgery Malign melanoma Lung cancers Renal cell carcinoma Radiotherapy Chemotherapy |
| url | http://www.scopemed.org/fulltextpdf.php?mno=46261 |
| work_keys_str_mv | AT ersinhaciyakupoglu metastaticbraintumors AT kadiroktay metastaticbraintumors AT semihkivancolguner metastaticbraintumors AT dervismansuriyilmaz metastaticbraintumors AT sebahattinhaciyakupoglu metastaticbraintumors |