Contributions of lipopolysaccharide and the type IVB secretion system to Coxiella burnetii vaccine efficacy and reactogenicity
Abstract Coxiella burnetii is the bacterial causative agent of the zoonosis Q fever. The current human Q fever vaccine, Q-VAX®, is a fixed, whole cell vaccine (WCV) licensed solely for use in Australia. C. burnetii WCV administration is associated with a dermal hypersensitivity reaction in people wi...
Main Authors: | Carrie M. Long, Paul A. Beare, Diane C. Cockrell, Jonathan Fintzi, Mahelat Tesfamariam, Carl I. Shaia, Robert A. Heinzen |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-03-01
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Series: | npj Vaccines |
Online Access: | https://doi.org/10.1038/s41541-021-00296-6 |
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