Radiation-Induced Fibrosis in Patients with Head and Neck Cancer: A Review of Pathogenesis and Clinical Outcomes
Radiotherapy-related fibrosis remains one of the most challenging treatment related side effects encountered by patients with head and neck cancer. Several established and ongoing novel therapies have been studied with paucity of data in how to best treat these patients. This review aims to provide...
Main Authors: | , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2022-01-01
|
Series: | Clinical Medicine Insights: Oncology |
Online Access: | https://doi.org/10.1177/11795549211036898 |
_version_ | 1811334406235750400 |
---|---|
author | Paul Ramia Larry Bodgi Dima Mahmoud Mohammad A Mohammad Bassem Youssef Neil Kopek Humaid Al-Shamsi Mona Dagher Ibrahim Abu-Gheida |
author_facet | Paul Ramia Larry Bodgi Dima Mahmoud Mohammad A Mohammad Bassem Youssef Neil Kopek Humaid Al-Shamsi Mona Dagher Ibrahim Abu-Gheida |
author_sort | Paul Ramia |
collection | DOAJ |
description | Radiotherapy-related fibrosis remains one of the most challenging treatment related side effects encountered by patients with head and neck cancer. Several established and ongoing novel therapies have been studied with paucity of data in how to best treat these patients. This review aims to provide researchers and health care providers with a comprehensive review on the presentation, etiology, and therapeutic options for this serious condition. |
first_indexed | 2024-04-13T17:07:25Z |
format | Article |
id | doaj.art-d0570b4d399e473688e8a245d67ba50a |
institution | Directory Open Access Journal |
issn | 1179-5549 |
language | English |
last_indexed | 2024-04-13T17:07:25Z |
publishDate | 2022-01-01 |
publisher | SAGE Publishing |
record_format | Article |
series | Clinical Medicine Insights: Oncology |
spelling | doaj.art-d0570b4d399e473688e8a245d67ba50a2022-12-22T02:38:25ZengSAGE PublishingClinical Medicine Insights: Oncology1179-55492022-01-011610.1177/11795549211036898Radiation-Induced Fibrosis in Patients with Head and Neck Cancer: A Review of Pathogenesis and Clinical OutcomesPaul Ramia0Larry Bodgi1Dima Mahmoud2Mohammad A Mohammad3Bassem Youssef4Neil Kopek5Humaid Al-Shamsi6Mona Dagher7Ibrahim Abu-Gheida8McGill University Health Centre, Montreal, QC, CanadaDepartment of Radiation Oncology, American University of Beirut Medical Center, Beirut, LebanonDepartment of Radiation Oncology, American University of Beirut Medical Center, Beirut, LebanonDepartment of Radiation Oncology, American University of Beirut Medical Center, Beirut, LebanonDepartment of Radiation Oncology, American University of Beirut Medical Center, Beirut, LebanonMcGill University Health Centre, Montreal, QC, CanadaUniversity of Sharjah, Sharjah, United Arab EmiratesDepartment of Radiation Oncology, American University of Beirut Medical Center, Beirut, LebanonUnited Arab Emirates University, Al Ain, United Arab EmiratesRadiotherapy-related fibrosis remains one of the most challenging treatment related side effects encountered by patients with head and neck cancer. Several established and ongoing novel therapies have been studied with paucity of data in how to best treat these patients. This review aims to provide researchers and health care providers with a comprehensive review on the presentation, etiology, and therapeutic options for this serious condition.https://doi.org/10.1177/11795549211036898 |
spellingShingle | Paul Ramia Larry Bodgi Dima Mahmoud Mohammad A Mohammad Bassem Youssef Neil Kopek Humaid Al-Shamsi Mona Dagher Ibrahim Abu-Gheida Radiation-Induced Fibrosis in Patients with Head and Neck Cancer: A Review of Pathogenesis and Clinical Outcomes Clinical Medicine Insights: Oncology |
title | Radiation-Induced Fibrosis in Patients with Head and Neck Cancer: A Review of Pathogenesis and Clinical Outcomes |
title_full | Radiation-Induced Fibrosis in Patients with Head and Neck Cancer: A Review of Pathogenesis and Clinical Outcomes |
title_fullStr | Radiation-Induced Fibrosis in Patients with Head and Neck Cancer: A Review of Pathogenesis and Clinical Outcomes |
title_full_unstemmed | Radiation-Induced Fibrosis in Patients with Head and Neck Cancer: A Review of Pathogenesis and Clinical Outcomes |
title_short | Radiation-Induced Fibrosis in Patients with Head and Neck Cancer: A Review of Pathogenesis and Clinical Outcomes |
title_sort | radiation induced fibrosis in patients with head and neck cancer a review of pathogenesis and clinical outcomes |
url | https://doi.org/10.1177/11795549211036898 |
work_keys_str_mv | AT paulramia radiationinducedfibrosisinpatientswithheadandneckcancerareviewofpathogenesisandclinicaloutcomes AT larrybodgi radiationinducedfibrosisinpatientswithheadandneckcancerareviewofpathogenesisandclinicaloutcomes AT dimamahmoud radiationinducedfibrosisinpatientswithheadandneckcancerareviewofpathogenesisandclinicaloutcomes AT mohammadamohammad radiationinducedfibrosisinpatientswithheadandneckcancerareviewofpathogenesisandclinicaloutcomes AT bassemyoussef radiationinducedfibrosisinpatientswithheadandneckcancerareviewofpathogenesisandclinicaloutcomes AT neilkopek radiationinducedfibrosisinpatientswithheadandneckcancerareviewofpathogenesisandclinicaloutcomes AT humaidalshamsi radiationinducedfibrosisinpatientswithheadandneckcancerareviewofpathogenesisandclinicaloutcomes AT monadagher radiationinducedfibrosisinpatientswithheadandneckcancerareviewofpathogenesisandclinicaloutcomes AT ibrahimabugheida radiationinducedfibrosisinpatientswithheadandneckcancerareviewofpathogenesisandclinicaloutcomes |