Biomimetic Hydroxyapatite on Graphene Supports for Biomedical Applications: A Review
Hydroxyapatite (HA) has been widely used in fields of materials science, tissue engineering, biomedicine, energy and environmental science, and analytical science due to its simple preparation, low-cost, and high biocompatibility. To overcome the weak mechanical properties of pure HA, various reinfo...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-10-01
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| Series: | Nanomaterials |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-4991/9/10/1435 |
| _version_ | 1818298233491816448 |
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| author | Gang Wei Coucong Gong Keke Hu Yabin Wang Yantu Zhang |
| author_facet | Gang Wei Coucong Gong Keke Hu Yabin Wang Yantu Zhang |
| author_sort | Gang Wei |
| collection | DOAJ |
| description | Hydroxyapatite (HA) has been widely used in fields of materials science, tissue engineering, biomedicine, energy and environmental science, and analytical science due to its simple preparation, low-cost, and high biocompatibility. To overcome the weak mechanical properties of pure HA, various reinforcing materials were incorporated with HA to form high-performance composite materials. Due to the unique structural, biological, electrical, mechanical, thermal, and optical properties, graphene has exhibited great potentials for supporting the biomimetic synthesis of HA. In this review, we present recent advance in the biomimetic synthesis of HA on graphene supports for biomedical applications. More focuses on the biomimetic synthesis methods of HA and HA on graphene supports, as well as the biomedical applications of biomimetic graphene-HA nanohybrids in drug delivery, cell growth, bone regeneration, biosensors, and antibacterial test are performed. We believe that this review is state-of-the-art, and it will be valuable for readers to understand the biomimetic synthesis mechanisms of HA and other bioactive minerals, at the same time it can inspire the design and synthesis of graphene-based novel nanomaterials for advanced applications. |
| first_indexed | 2024-12-13T04:32:04Z |
| format | Article |
| id | doaj.art-d059df4e760046b891f618492f35d963 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-12-13T04:32:04Z |
| publishDate | 2019-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-d059df4e760046b891f618492f35d9632022-12-21T23:59:31ZengMDPI AGNanomaterials2079-49912019-10-01910143510.3390/nano9101435nano9101435Biomimetic Hydroxyapatite on Graphene Supports for Biomedical Applications: A ReviewGang Wei0Coucong Gong1Keke Hu2Yabin Wang3Yantu Zhang4College of Chemistry & Chemical Engineering, Yan’an University, Yan’an 716000, ChinaFaculty of Production Engineering, University of Bremen, D-28359 Bremen, GermanyCollege of Chemistry & Chemical Engineering, Yan’an University, Yan’an 716000, ChinaCollege of Chemistry & Chemical Engineering, Yan’an University, Yan’an 716000, ChinaCollege of Chemistry & Chemical Engineering, Yan’an University, Yan’an 716000, ChinaHydroxyapatite (HA) has been widely used in fields of materials science, tissue engineering, biomedicine, energy and environmental science, and analytical science due to its simple preparation, low-cost, and high biocompatibility. To overcome the weak mechanical properties of pure HA, various reinforcing materials were incorporated with HA to form high-performance composite materials. Due to the unique structural, biological, electrical, mechanical, thermal, and optical properties, graphene has exhibited great potentials for supporting the biomimetic synthesis of HA. In this review, we present recent advance in the biomimetic synthesis of HA on graphene supports for biomedical applications. More focuses on the biomimetic synthesis methods of HA and HA on graphene supports, as well as the biomedical applications of biomimetic graphene-HA nanohybrids in drug delivery, cell growth, bone regeneration, biosensors, and antibacterial test are performed. We believe that this review is state-of-the-art, and it will be valuable for readers to understand the biomimetic synthesis mechanisms of HA and other bioactive minerals, at the same time it can inspire the design and synthesis of graphene-based novel nanomaterials for advanced applications.https://www.mdpi.com/2079-4991/9/10/1435graphenehydroxyapatitebiomimetic synthesisnanohybridsbiomedical applications |
| spellingShingle | Gang Wei Coucong Gong Keke Hu Yabin Wang Yantu Zhang Biomimetic Hydroxyapatite on Graphene Supports for Biomedical Applications: A Review Nanomaterials graphene hydroxyapatite biomimetic synthesis nanohybrids biomedical applications |
| title | Biomimetic Hydroxyapatite on Graphene Supports for Biomedical Applications: A Review |
| title_full | Biomimetic Hydroxyapatite on Graphene Supports for Biomedical Applications: A Review |
| title_fullStr | Biomimetic Hydroxyapatite on Graphene Supports for Biomedical Applications: A Review |
| title_full_unstemmed | Biomimetic Hydroxyapatite on Graphene Supports for Biomedical Applications: A Review |
| title_short | Biomimetic Hydroxyapatite on Graphene Supports for Biomedical Applications: A Review |
| title_sort | biomimetic hydroxyapatite on graphene supports for biomedical applications a review |
| topic | graphene hydroxyapatite biomimetic synthesis nanohybrids biomedical applications |
| url | https://www.mdpi.com/2079-4991/9/10/1435 |
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