Enhanced ε-Poly-L-Lysine Production by the Synergistic Effect of ε-Poly-L-Lysine Synthetase Overexpression and Citrate in Streptomyces albulus
ε-Poly-L-lysine (ε-PL) is a natural amino acid polymer produced by microbial fermentation. It has been mainly used as a preservative in the food and cosmetics industries, as a drug carrier in medicines, and as a gene carrier in gene therapy. ε-PL synthase is the key enzyme responsible for the polyme...
Main Authors: | Aixia Wang, Wenzhe Tian, Lei Cheng, Youqiang Xu, Xiuwen Wang, Jiayang Qin, Bo Yu |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-04-01
|
Series: | Frontiers in Bioengineering and Biotechnology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fbioe.2020.00288/full |
Similar Items
-
AdpA, a developmental regulator, promotes ε-poly-l-lysine biosynthesis in Streptomyces albulus
by: Rui Huang, et al.
Published: (2022-04-01) -
Engineering Streptomyces albulus to enhance ε-poly-L-lysine production by introducing a polyphosphate kinase-mediated ATP regeneration system
by: Hao Yang, et al.
Published: (2023-03-01) -
Improved Production of ε-Poly-L-Lysine in Streptomyces albulus Using Genome Shuffling and Its High-Yield Mechanism Analysis
by: Yongjuan Liu, et al.
Published: (2022-05-01) -
Identification and Combinatorial Overexpression of Key Genes for Enhancing ε-Poly-L-lysine Biosynthesis in <i>Streptomyces albulus</i>
by: Hongjian Zhang, et al.
Published: (2024-01-01) -
Advances in Strain Improvement for the Production of ε-Poly-L-lysine
by: SUN Zilong, FU Jiaolong, WANG Yue, ZHOU Yunfeng, LI Boyan, QIAN Wei, BAI Jing, JU Xin, LI Liangzhi
Published: (2023-12-01)